Results 11 to 20 of about 25,429 (197)

Distinctive Effects of Cytochalasin B in Chick Primary Myoblasts and Fibroblasts. [PDF]

PLoS ONE, 2016
Actin-based structures play fundamental roles in cellular functions. However it remains controversial how cells cope with the absence of F-actin structures.
Koichi Ojima, Zhong-Xiang Lin, Ivone Rosa de Andrade, Manoel Luis Costa, Claudia Mermelstein   +4 more
doaj   +2 more sources

Effect of chemotherapeutic drugs and cytochalasin B on tunneling nanotubes in U87 MG cells [PDF]

BMC Cancer
Intercellular communication in the tumor microenvironment has a major impact on therapeutic outcomes. In particular, highly aggressive cancers such as glioblastoma benefit from efficient cellular communication by developing resistance to therapy or by ...
Nicole Matejka, Jessica Neubauer, Judith Reindl   +2 more
doaj   +2 more sources

Testing Strategies of the In Vitro Micronucleus Assay for the Genotoxicity Assessment of Nanomaterials in BEAS-2B Cells

Nanomaterials, 2021
The evaluation of the frequency of micronuclei (MN) is a broadly utilised approach in in vitro toxicity testing. Nevertheless, the specific properties of nanomaterials (NMs) give rise to concerns regarding the optimal methodological variants of the MN ...
Tereza Cervena, Andrea Rossnerova, Tana Zavodna, Jitka Sikorova, Kristyna Vrbova, Alena Milcova, Jan Topinka, Pavel Rossner   +7 more
doaj   +1 more source

Resolution of the Hypoxylon fuscum Complex (Hypoxylaceae, Xylariales) and Discovery and Biological Characterization of Two of Its Prominent Secondary Metabolites

Journal of Fungi, 2021
Hypoxylon, a large, cosmopolitan genus of Ascomycota is in the focus of our current poly-thetic taxonomic studies, and served as an excellent source for bioactive secondary metabolites at the same time. The present work concerns a survey of the Hypoxylon
Christopher Lambert, Mohammad Javad Pourmoghaddam, Marjorie Cedeño-Sanchez, Frank Surup, Seyed Akbar Khodaparast, Irmgard Krisai-Greilhuber, Hermann Voglmayr, Theresia E. B. Stradal, Marc Stadler   +8 more
doaj   +1 more source

Bacterial Engulfment Mechanism Is Strongly Conserved in Evolution Between Earthworm and Human Immune Cells

Frontiers in Immunology, 2021
Invertebrates, including earthworms, are applied to study the evolutionarily conserved cellular immune processes. Earthworm immunocytes (so-called coelomocytes) are functionally similar to vertebrate myeloid cells and form the first line of defense ...
Bohdana Kokhanyuk, Kornélia Bodó, György Sétáló Jr, György Sétáló Jr, Péter Németh, Péter Engelmann   +5 more
doaj   +1 more source

Quantitative Analysis of the Cytoskeleton’s Role in Inward Rectifier KIR2.1 Forward and Backward Trafficking

Frontiers in Physiology, 2022
Alteration of the inward rectifier current IK1, carried by KIR2.1 channels, affects action potential duration, impacts resting membrane stability and associates with cardiac arrhythmias.
Encan Li, Vera Loen, Willem B. van Ham, Willy Kool, Marcel A. G. van der Heyden, Hiroki Takanari   +5 more
doaj   +1 more source

Recovery of aging-related size increase of skin epithelial cells: in vivo mouse and in vitro human study. [PDF]

PLoS ONE, 2015
The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially decreases cell size.
Igor Sokolov, Natali V Guz, Swaminathan Iyer, Amy Hewitt, Nina A Sokolov, Joseph S Erlichman, Craig D Woodworth   +6 more
doaj   +1 more source

Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle

Journal of Pharmacological Sciences, 2020
The role of cytoskeleton dynamics in the oxidative stress toward human vasculature has been unclear. The current study examined whether the cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial
Kazumi Takaishi, Hiroyuki Kinoshita, Guo-Gang Feng, Toshiharu Azma, Shinji Kawahito, Hiroshi Kitahata   +5 more
doaj   +1 more source

Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation

Journal of Fungi, 2022
Laying the groundwork on preliminary structure–activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fungus ...
Katherine Yasmin M. Garcia, Mark Tristan J. Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E. B. Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G. Macabeo   +11 more
doaj   +1 more source

Myosin V and iNOS expression is enhanced in J774 murine macrophages treated with IFN-gamma [PDF]

Brazilian Journal of Medical and Biological Research, 2001
Actin-based motor protein requirements and nitric oxide (NO) production are important features of macrophage activity during phagocytosis or microbicidal processes.
D.S. Reis, M.A. Souza, J.R. Mineo, F.S. Espindola   +3 more
doaj   +1 more source