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Actin and vimentin jointly control cell viscoelasticity and compression stiffening
Conboy JP +4 more
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Teratogenicity of cytochalasin D in the mouse
Teratology, 1977AbstractCytochalasin D, a mold metabolite identified in food, was injected intraperitoneally in doses of 0.4 to 0.9 mg per kilogram on gestational days 7 through 11 and produced evidence of teratogenicity in two out of three strains of mice. Exencephaly, hypognathia and axial skeletal defects were found in strains C57BL/6J and BALB/c while no increase ...
Shepard, T H, Greenaway, J C
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Cytochalasin D‐induced triploidy in the mouse
Journal of Experimental Zoology, 1989AbstractPrevious attempts to obtain digynic triploid mouse development in vivo have either been entirely or only marginally successful, generally with the production of heteroploid rather than triploid conceptuses. We report that when a single intraperitoneal injection of 15 üg of cytochalasin D is given to recently mated female mice during a ...
S. Speirs, M. H. Kaufman
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Selektive Reaktionen an Cytochalasin D
Helvetica Chimica Acta, 1982AbstractIn connection with the total synthesis of cytochalasans the cleavage of the macrocyclic system of cytochalasin D (3) was studied in order to gain useful relay compounds. Selective scission of the double bond in 19‐position was achieved by controlled ozonolysis leading to compound 7 (Scheme 1). Treatment of 3 with OsO4 and subsequent acetylation
Georges Chappuis, Christoph Tamm
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Structures of cytochalasins C and D
Journal of the Chemical Society C: Organic, 1969The structures of cytochalasins C and D, metabolites of Metarrhizium anisopliae, have been determined.
D. C. Aldridge, W. B. Turner
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The binding of cytochalasin D to monomeric actin
Biochemical and Biophysical Research Communications, 1985The binding of cytochalasin D to monomeric actin has been measured directly. In the presence of 200 microM Ca2+, actin binds cytochalasin D in a 1:1 molar ratio with a KD of 18 microM. After incubation with 250 microM Mg2+ for 10 minutes, actin binds cytochalasin D with a KD of 2.6 microM but with one mole of cytochalasin D per 2 moles of actin.
Dean Goddette, Carl Frieden
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Acceleration of Peritoneal Solute Transport by Cytochalasin D
Uremia Investigation, 1984Because cytochalasin D affects intercellular junctions the effect of this agent on peritoneal transport was investigated in normal rabbits. Using commercially available dialysis solution, short-term control peritoneal dialyses were compared in the same animals to dialyses in which cytochalasin D was added intraperitoneally.
John F. Maher +2 more
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Cytochalasin D fromHypocrella Bambusae
Journal of Asian Natural Products Research, 2001Cytochalasin D which shows marked cytotoxic effects on multi-tumor cells was newly isolated at high content(5.28 mg/g, dry weight) from Fungus Hypocrella bambusae(B.et Br.) Sacc. Its structure was elucidated by spectroscopic methods. Two-dimensional NMR techniques were applied to make complete assignment for the 1H- and 13C-NMR chemical shifts of this ...
Ke-Di Cheng +4 more
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Total synthesis of cytochalasin D: total synthesis and full structural assignment of cytochalasin O [PDF]
Journal of the Chemical Society, Perkin Transactions 1, 1999 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Eric J. Thomas, Eric Merifield
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Cytochalasin D abolishes the schistosomicidal activity of praziquantel
Experimental Parasitology, 2007To test the hypothesis that calcium channels of schistosomes are the targets for the action of praziquantel, we subjected schistosomes in vitro to pharmacological agents capable of interfering with the functioning of calcium channels. After 1-h exposure to these agents, praziquantel was added and incubation continued overnight.
PicaMattoccia L +7 more
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