Results 211 to 220 of about 330,393 (233)

The binding sites of cytochalasin D. II. Their relationship to hexose transport and to cytochalasin B

Journal of Cellular Physiology, 1977
AbstractCytochalasin B (CB) was able to compete with tritiated cytochalasin D (3H‐CD) for binding sites in HEp‐2 cells. The pattern of inhibition suggested that CB associates with a low affinity class of CD binding sites. Glucose and maltose did not inhibit binding of 3H‐CD to isolated HEp‐2 plasma membrane.
Janet Tannenbaum, Gabriel C. Godman, Stuart W. Tanenbaum   +2 more
openaire   +3 more sources

Binding and subcellular localization of tritiated cytochalasin D

Experimental Cell Research, 1975
Abstract Tritiated cytochalasin D ( 3 H-CD) is rapidly taken up by monolayers of HEp-2 HeLa and rhabdomyosarcoma cells, reaching a maximum incorporation within 5 min at 37 °C. Upon rinsing and refeeding, 80% of the bound drug rapidly dissociates from the cells; the remaining 20 % is lost more slowly. Binding is dose-dependent in a non-linear fashion;
Janet Tannenbaum, Gabriel C. Godman, Armand F. Miranda, L.W. Lo, Stuart W. Tanenbaum   +4 more
openaire   +3 more sources

Effect of cytochalasin D on smooth muscle contraction

Cell Motility, 1983
AbstractCylindrical segments of extraparenchymal pulmonary artery (essentially a preparation of smooth muscle with regard to contractile capability) were isolated from adult male rats. They were mounted in an isometric muscle bath in physiological salt solution (PSS) in an environment of 95% O2/ CO2.
Judith Krill, John N. Evans, Kenneth B. Adler, Tod V. Alberghini   +3 more
openaire   +3 more sources

Vitamin C reduces cytochalasin D cataractogenesis

Current Eye Research, 1995
The effect of cytochalasin D (CD), an actin monomer-stabilizer, has been studied on cataract development in rat lenses. Cataractogenesis was induced by incubating the rat lenses in medium 199 (M199) containing 10(-5) M CD; by the end of 24 h, lenses first developed a visible opacity.
John R. Trevithick, Fusun Kilic
openaire   +3 more sources

Cytochalasin D reversibly weakens retinal adhesiveness

Current Eye Research, 1995
This study asks whether retinal adhesiveness is affected by cytochalasin D, a drug that is known to alter the apical morphology of the retinal pigment epithelium (RPE). Cytochalasin D was injected intravitreally in Dutch rabbits and retinal adhesiveness measured 0.5 to 72 h later by two methods: in vitro peeling of the retina from retinal pigment ...
Roopa Dalal, A Takeuchi, Michael F. Marmor, Xiao-Ying Yao, Robert Kent Chiang   +4 more
openaire   +3 more sources

The effects of cytochalasin D on differentiating muscle in culture

Tissue and Cell, 1973
Abstract The spontaneous contractility of myotubes is enhanced by cytochalasin D (CD), which also causes myotobes to constrict and retract. Within an hour, large accumulations of filament masses appear in the cortical cytoplasm; they are later sequestered by fusion of sarcoplasmic membranes.
Gabriel C. Godman, Armand F. Miranda
openaire   +3 more sources

ChemInform Abstract: SELECTIVE REACTIONS OF CYTOCHALASIN D

Chemischer Informationsdienst, 1982
AbstractUm Synthone für den Aufbau von Cytochalasanen zu gewinnen, werden Abbau‐Reaktionen von Cytochalasin D (Ia) untersucht.
G. Chappuis, C. Tamm
openaire   +2 more sources

The morphology of cytoplasts and karyoplasts produced by cytochalasin D

Experientia, 1979
The denucleation of L cells and human lymphocytes in suspension was carried out by incubation with cytochalasin D25 and 50 microgram/ml and with ultracentrifugation over a discontinuous Ficoll gradient. Ultrastructural examination of the separate layers confirmed the presence of the anucleate cytoplasm (cytoplasts) with intact membrane and the ...
openaire   +3 more sources

Structure-activity correlations of cytochalasins. Novel halogenated and related cytochalasin C and D derivatives

Journal of Medicinal Chemistry, 1982
AbstractDie Bromierung von Cytochalasin D (CD) (I) mit Phenyltrimethylammoniumtribromid liefert das 6,12‐Dibromo‐CD (II).
Michael Flashner, Stuart W. Tanenbaum, Carl A. Miller, Bhalchandra H. Patwardhan   +3 more
openaire   +4 more sources

The cortical actomyosin system of cytochalasin D-treated lymphoblasts

Experimental Cell Research, 1991
Global cytoskeleton dynamics is likely to exist in animal cells and some experimental evidence for this has recently been obtained in cells from the human lymphoblastic cell line KE37. We have further investigated the dramatic and reversible microtubule-dependent cell elongation which occurs upon treatment of KE37 cells with cytochalasin D.
Claude Celati, Eric Bailly, Michel Bornens   +2 more
openaire   +3 more sources