Frontiers in Immunology, 2021 Invertebrates, including earthworms, are applied to study the evolutionarily conserved cellular immune processes. Earthworm immunocytes (so-called coelomocytes) are functionally similar to vertebrate myeloid cells and form the first line of defense ...
Bohdana Kokhanyuk +5 more
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Cytoskeletal Remodeling Mimics Endothelial Response to Microgravity
Frontiers in Cell and Developmental Biology, 2021 Mechanical cues contribute to the maintenance of a healthy endothelium, which is essential for vascular integrity. Indeed endothelial cells are mechanosensors that integrate the forces in the form of biochemical signals.
Laura Locatelli +2 more
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YAP/TAZ regulates the expression of proteoglycan 4 and tenascin C in superficial-zone chondrocytes [PDF]
European Cells & Materials, 2020 The roles of cell division control protein 42 homologue (CDC42) and actin polymerisation in regulating the phenotype of superficial-zone chondrocytes (SZCs) have been demonstrated in vitro; however, the signalling pathway(s) downstream have yet to be ...
E Delve +5 more
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TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. [PDF]
PLoS ONE, 2015 TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown.
Andreas Schwingshackl +3 more
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Cell contractile force measured using a deformable hollow capsule
The EuroBiotech Journal, 2022 There are several possible ways to measure the contraction of cells in vitro. Here, we report measurements of the contractile properties of 3T3-L1 cells grown to confluence on 3D hollow capsules.
Ting Julia Ho Yee, Martin Donald K
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Quantitative image mean squared displacement (iMSD) analysis of the dynamics of profilin 1 at the membrane of live cells. [PDF]
, 2018 Image mean square displacement analysis (iMSD) is a method allowing the mapping of diffusion dynamics of molecules in living cells. However, it can also be used to obtain quantitative information on the diffusion processes of fluorescently labelled ...
Davey, Rhonda J +3 more
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Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes
Journal of Orthopaedic Surgery and Research, 2022 Background Mechanical loading has been widely considered to be essential for growth plate to maintain metabolism and development. Cyclic mechanical strain has been demonstrated to induce autophagy, whereas the relationship between cyclic tensile strain ...
Jin-ming Zhang +6 more
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The Modulation of Functional Status of Bovine Spermatozoa by Progesterone
Animals, 2021 The aim of this study is to identify the effects of progesterone (PRG) on the capacitation and the acrosome reaction in bovine spermatozoa. The fresh sperm samples were incubated with and without capacitation inductors (heparin, dibutyryl cyclic ...
Vitaly Denisenko +5 more
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Modulation of the extracellular matrix patterning of thrombospondins by actin dynamics and thrombospondin oligomer state [PDF]
, 2015 Thrombospondins (TSPs) are evolutionarily-conserved, secreted glycoproteins that interact with cell surfaces and extracellular matrix (ECM) and have complex roles in cell interactions.
Adams, Josephine C +4 more
core +2 more sources