Results 111 to 120 of about 778,750 (338)

Engineering Electron Transfer Flux between Cytochrome P450 Enzyme and P450 Reductase to Enhance Serotonin Production in Escherichia Coli

Advanced Science, EarlyView.
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu, Pengling Wei, Lirong Chen, Ling Gao, Xiaole Xia   +4 more
wiley   +1 more source

Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats

Drug Design, Development and Therapy, 2021
Yong Shi,1,* Deru Meng,1,* Shuanghu Wang,1 Peiwu Geng,1 Tao Xu,2 Quan Zhou,1 Yunfang Zhou,1 Wanshu Li,3 Xugao Chen4 1Comprehensive Breast Health Center, Department of Thyroid and Breast Surgery, The Sixth Affiliated Hospital of Wenzhou Medical ...
Shi Y, Meng D, Wang S, Geng P, Xu T, Zhou Q, Zhou Y, Li W, Chen X   +8 more
doaj  

Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet

Advanced Science, EarlyView.
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang, Lianhuang Li, Janet E. Sorrells, Jianxin Chen, Haohua Tu   +4 more
wiley   +1 more source

THE POSITION OF THE CELL NUCLEUS IN PATHWAYS OF HYDROGEN TRANSFER: CYTOCHROME C, FLAVOPROTEINS, GLUTATHIONE, AND ASCORBIC ACID [PDF]

, 1954
Herbert Stern, Sari Timonen
openalex   +1 more source

From Code to Life: The AI‐Driven Revolution in Genome Editing

Advanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen   +10 more
wiley   +1 more source

QcrC is a potential target for antibody therapy and vaccination to control Campylobacter jejuni infection by suppressing its energy metabolism

Frontiers in Microbiology
IntroductionCampylobacter spp. are a public health concern, yet there is still no effective vaccine or medicine available.MethodsHere, we developed a Campylobacter jejuni-specific antibody and found that it targeted a menaquinol cytochrome c reductase ...
Koji Hosomi, Koji Hosomi, Noritoshi Hatanaka, Noritoshi Hatanaka, Noritoshi Hatanaka, Atsushi Hinenoya, Atsushi Hinenoya, Atsushi Hinenoya, Jun Adachi, Yoko Tojima, Yoko Tojima, Mari Furuta, Mari Furuta, Keita Uchiyama, Keita Uchiyama, Makiko Morita, Makiko Morita, Takahiro Nagatake, Takahiro Nagatake, Azusa Saika, Azusa Saika, Soichiro Kawai, Soichiro Kawai, Ken Yoshii, Ken Yoshii, Saki Kondo, Saki Kondo, Shinji Yamasaki, Shinji Yamasaki, Shinji Yamasaki, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa, Jun Kunisawa   +38 more
doaj   +1 more source

An Exploration of the Sub-Register of Chemical Engineering Research Papers Published in English

Publications, 2018
The increased pressures for high-volume, high-impact publications in English language and the high rejection rates of submitted manuscripts for publications present an often unsurpassable obstacle for (early career) researchers.
Myrto-Panagiota Zacharof, Anna Charalambidou   +1 more
doaj   +1 more source

The chromatographic behaviour of cytochrome c on cation exchangers [PDF]

, 1954
E. Margoliash
openalex   +1 more source

Label‐Free 3D Photoacoustic Imaging of Tumor Organoids for Volumetric Drug Screening

Advanced Science, EarlyView.
A label‐free organoid photoacoustic imaging (LFOPI) system is developed for precise volumetric drug screening evaluation. As a proof of concept, LFOPI's performance in chemotherapy and immunotherapy drug screening assays are further evaluated. The LFOPI offers unique non‐invasive, label‐free capabilities for tumor organoids, and contributes to the ...
Xiaofei Luo, Maike Chen, Han Shan, Xize Yu, Qibo Lin, Qian Tao, Xiongwei Wei, Changling Lv, Ziyan Chen, Fan Zhuo, Xi Zhu, Jiaxing He, Zhaoxi Li, Chunlong Fei, Jing Xu, Juan Su, Zeyu Chen, Shuang Zhao, Xiang Chen   +18 more
wiley   +1 more source

Cytochrome “nanowires” are physically limited to sub-picoamp currents that suffice for cellular respiration

Frontiers in Chemistry
Mineral-respiring microorganisms from hydrothermal vents to terrestrial soils express filaments that electrically connect intracellular respiration to extracellular geochemistry. Filaments dubbed “cytochrome nanowires” (CNs) have been resolved by CryoEM,
Matthew J. Guberman-Pfeffer, Caleb L. Herron   +1 more
doaj   +1 more source