Results 161 to 170 of about 391,026 (214)

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

Detection of Batborne Hantaviruses, Laos, 2023-2024. [PDF]

Emerg Infect Dis
Vanhnollat C, Somlor S, Dimitrova K, Medina S, Vongphayloth K, Vungkyly V, Vachouaxiong L, Douangboubpha B, Sanamxay D, Xayaphet V, Paphaphanh P, Theppangna W, Audet J, Buchy P, Safronetz D.   +14 more
europepmc   +1 more source

Caffeine-clarithromycin coadministration and hyperlactatemia in a young infant: a case report. [PDF]

Crit Care Sci
Volpon LC, Costa FM, Carlotti APCP.
europepmc   +1 more source

Use of Whole Cells and Cell‐Free Extracts of Catalase‐Deficient E. coli for Peroxygenase‐Catalyzed Reactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Unspecific peroxygenases (UPOs) and cytochrome P450 monooxygenases (CYPs) with peroxygenase activity are becoming the preferred biocatalysts for oxyfunctionalization reactions. While whole cells (WCs) or cell‐free extracts (CFEs) of Escherichia coli are often preferred for cofactor‐dependent monooxygenase reactions, hydrogen peroxide (H2O2 ...
Ana C. Ebrecht, U. Joost Luelf, Kamini Govender, Diederik J. Opperman, Vlada B. Urlacher, Martha S. Smit   +5 more
wiley   +1 more source

Investigation of the Presence of Papillomavirus in Bovine Testicles and Determination of γH2AX and Cytochrome C in Testicular Tissues Determined to be Infected. [PDF]

Vet Med Sci
Karatas O, Ozkaraca M, Atasoy MO.
europepmc   +1 more source

Altering 15‐Lipoxygenases to 18‐Lipoxygenases and Their Application to the Production of 5,18‐Dihydroxyeicosapentaenoic Acids

Biotechnology and Bioengineering, EarlyView.
15R‐ and 15S‐lipoxygenases (15R‐ and 15S‐LOXs) were engineered into 18R‐ and 18S‐LOXs, respectively. Escherichia coli expressing these enzymes converted eicosapentaenoic acid into 18R‐ and 18S‐hydroxyeicosapentaenoic acids (18R‐ and 18S‐HEPEs), respectively.
Jin Lee, Su‐Hwan Kang, Tae‐Eui Lee, Deok‐Kun Oh   +3 more
wiley   +1 more source

Strategies to combat cancer drug resistance: focus on copper metabolism and cuproptosis. [PDF]

Cancer Drug Resist
Yao L, Jiang B, Xu D.
europepmc   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen, Shijie Shangguan, Zhongyu Lin, Xuemei Zeng, Siew Yin Chan, Xian Qin, Shuangqian Yan   +6 more
wiley   +1 more source

Pulling back the mitochondria's iron curtain. [PDF]

NPJ Metab Health Dis
Ben Zichri-David S, Shkuri L, Ast T.
europepmc   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source