Pilze haben zweimal unabhängig gelernt, Psilocybin, den ikonischen Naturstoff der Zauberpilze, herzustellen. Dieser Artikel stellt die Enzyme des zweiten Biosyntheseweges vor, der in einem Risspilz gefunden wurde. Verblüffenderweise stimmen die beiden Wege in keiner Reaktion überein.
Tim Schäfer +3 more
wiley +1 more source
A bioinspired MnFe porphyrrole aerogel catalyst is synthesized using a covalent 3D framework with adjacent metal centers. The bimetallic structure enhances ORR activity through Mn─Fe synergy and high active site density. Fuel cell tests show over a 30% increase in peak power density, with DFT calculations confirming metal–metal charge transfer as the ...
Eliana Lebowitz +7 more
wiley +2 more sources
An Orthogonal Supramolecular Approach toward Protein Binding and Protein Sensing Using Dendrimers as Scaffolds for the Noncovalent Assembly of Binding and Sensing Groups. [PDF]
Aziz A +4 more
europepmc +1 more source
Synthesis and Application of Bioactive N‐Functionalized Aziridines
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan +4 more
wiley +2 more sources
Physiologically Based Pharmacokinetic Modeling of Valemetostat to Inform Dose Recommendations When Coadministered With CYP3A/P-gp Modulators. [PDF]
Watanabe A +6 more
europepmc +1 more source
The porphyrin of component c of cytochrome and its relationship to other porphyrins
Robert D. Hill, D. Keilin
openalex +1 more source
Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova +3 more
wiley +2 more sources
Molecular insights into <i>Aedes aegypti</i> (L.) populations and vector surveillance in the urban areas of Jeddah and Jizan, Saudi Arabia. [PDF]
Alqurashi SI +8 more
europepmc +1 more source
Breakthroughs in the development of antibiotics, antifungals and antiparasitics targeting the pathogens' respiratory chain. [PDF]
Sorescu JM +9 more
europepmc +1 more source

