Genomic and Transcriptomic Insights Into the Autotrophic Metabolism on H<sub>2</sub> + CO<sub>2</sub> or CO of the Thermophilic Acetogenic Model Organism Moorella thermoacetica. [PDF]
Rosenbaum FP +3 more
europepmc +1 more source
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh +5 more
wiley +1 more source
Parallel Valet Parking: Selective Ion Escape over an AC Barrier During Ion/ion Reactions in a Quadrupole Linear Ion Trap. [PDF]
Horn SA, Pizzala NJ, McLuckey SA.
europepmc +1 more source
Ligand architecture and secondary‐sphere effects in a well‐defined cobalt(IV)–oxo complex
A well‐defined cobalt(IV)–oxo complex supported by a neutral tetraazamacrocyclic ligand is generated and fully characterized. The cobalt(IV)–oxo species exhibits electrophilic oxygen‐atom and hydrogen‐atom transfer reactivity, strongly modulated by protonation and secondary coordination sphere effects, providing new insight into structure–reactivity ...
Ying Xing +3 more
wiley +1 more source
Lipid Dependence of CYP3A4 Activity in Nanodiscs. [PDF]
Denisov IG, Grinkova YV, Sligar SG.
europepmc +1 more source
ABSTRACT Laboratory science education can provide a training ground for developing experimental design capabilities, the ability to critically assess a range of laboratory methods, and confidence in selecting, adapting, and performing laboratory techniques.
Nathan D. Tivendale +2 more
wiley +1 more source
A Cytochrome c-Containing Periplasmic Nitrate Reductase in the Acetogen Sporomusa ovata. [PDF]
Waschinger LM +4 more
europepmc +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Cytosolic cytochrome c represses ferroptosis. [PDF]
Song X +11 more
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source

