Results 71 to 80 of about 414,611 (257)
No abstract ...
von Jagow, Gerhard, Sebald, Walter
openaire +3 more sources
A comparative genomic analysis of energy metabolism in sulfate reducing bacteria and archaea
The number of sequenced genomes of sulfate-reducing organisms (SRO) has increased significantly in the recent years, providing an opportunity for a broader perspective into the energy metabolism of such organisms.
Inês A. C. ePereira +5 more
doaj +1 more source
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang +22 more
wiley +1 more source
Cytochrome c binding affects the conformation of cytochrome a in cytochrome c oxidase.
Second derivative absorption spectroscopy has been used to assess the effects of complex formation between cytochrome c and cytochrome c oxidase on the conformation of the cytochrome a cofactor. When ferrocytochrome c is complexed to the cyanide-inhibited reduced or mixed valence enzyme, the conformation of ferrocytochrome a is affected.
S R, Lynch, D, Sherman, R A, Copeland
openaire +2 more sources
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source
Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats
Yong Shi,1,* Deru Meng,1,* Shuanghu Wang,1 Peiwu Geng,1 Tao Xu,2 Quan Zhou,1 Yunfang Zhou,1 Wanshu Li,3 Xugao Chen4 1Comprehensive Breast Health Center, Department of Thyroid and Breast Surgery, The Sixth Affiliated Hospital of Wenzhou Medical ...
Shi Y +8 more
doaj
An Exploration of the Sub-Register of Chemical Engineering Research Papers Published in English
The increased pressures for high-volume, high-impact publications in English language and the high rejection rates of submitted manuscripts for publications present an often unsurpassable obstacle for (early career) researchers.
Myrto-Panagiota Zacharof +1 more
doaj +1 more source
Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang +6 more
wiley +1 more source
HIGH DOSES OF IVERMECTIN CAUSE TOXIC EFFECTS AFTER SHORTTERM ORAL ADMINISTRATION IN RATS
The anthelmintic macrocyclic lactones (MLs) are the most important endectocides in modern pharmacotherapy of parasitic infections. However, during the COVID 19 pandemic, ivermectin was used in humans against infection with the SARS-CoV-2 virus in doses ...
Vladimir Marjanović +9 more
doaj +1 more source
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li +23 more
wiley +1 more source

