Results 41 to 50 of about 383,545 (307)

The role of cytochrome b 5 fusion desaturases in the synthesis of polyunsaturated fatty acids

, 2003
The biosynthetic pathway of polyunsaturated fatty acids (PUFAs) has been the subject of much interest over the last few years. Significant progress has been made in the identification of the enzymes required for PUFA synthesis; in particular, the fatty ...
Sayanova, O. V., Michaelson, L. V., Napier, J. A.   +2 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

New records of Oryzomys couesi (Alston, 1877) (Cricetidae, Rodentia) in Colombia, with remarks on its taxonomy, morphology, and geographic distribution [PDF]

Check List
Oryzomys couesi (Alston, 1877) has a restricted geographic distribution in South America. Until now, it was only known from Montería, Córdoba, in the Caribbean region of Colombia.
Sergio Solari, Sebastián Cifuentes-Acevedo, Laura M. Aramendiz-Macías   +2 more
doaj   +3 more sources

Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily.

, 2012
The known subunits of yeast mitochondrial cytochrome c oxidase are reviewed. The structures of all eleven of its subunits are explored by building homology models based on the published structures of the homologous bovine subunits and similarities and ...
Maréchal, A, Orengo, Christine, Amandine Maréchal, Peter R. Rich, Brigitte Meunier, Lee, David, Lee, D, Meunier, Brigitte, Maréchal, Amandine, Orengo, C, Meunier, B, Rich, Peter R., Christine Orengo, David Lee, Rich, PR   +14 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cytochrome-b_alignment_Abrothrix_manni

, 2018
DNA sequences of the first 801bp of the gene Cytochrome-b of specimens of Abrothrix manni. This is a non-redundant alignment, i.e., only one sequence representative of each haplotypic class is included.
Valdez, Lourdes, Lourdes Valdez (720485), D'Elía, Guillermo, Guillermo D'Elía (116684)   +3 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Genetic and Morphological Diversity of Tenthredopsis (Tenthredinidae: Symphyta: Hymenoptera) Species: A Case Study in Anatolia

Cumhuriyet Science Journal
The genus Tenthredopsis (Tenthredinidae: Hymenoptera), characterized by a Palearctic distribution, is widely recognized as a taxonomic challenge due to its limited morphological variation.
Sevda Hastaoğlu Örgen, Hasan Hüseyin Başıbüyük   +1 more
doaj   +1 more source

Possible Application of Cytochrome b Gene for Human Identification

Arab Journal of Forensic Sciences & Forensic Medicine, 2015
The mitochondrial cytochrome b gene (cytb) has been partially amplified and sequenced in order to identify the characteristic SNPs (single nucleotide polymorphism) for some Saudi Arabian tribes.
Sayed A.M. Amer, Bandar AlHothali, Salah M. A. Tubaigy   +2 more
doaj   +1 more source