We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Rapid identification of European (Anguilla anguilla) and North American eel (Anguilla rostrata) by polymerase chain reaction. [PDF]
A rapid and cost effective DNA test is described to identify European eel (Anguilla anguilla) and North American eel (Anguilla rostrata). By means of polymerase chain reaction (PCR) technique parts of the mitochondrial cytochrome b gene are amplified ...
Trautner, Jochen
core
Intersex related gene expression profiles in clams Scrobicularia plana : molecular markers and environmental application [PDF]
Intersex, the appearance of female characteristics in male gonads, has been identified in several aquatic species. It is a widespread phenomenon in populations of the bivalve, Scrobicularia plana, from the southwest coast of the U.K.
Alvarez-Munoz, Diana +14 more
core +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout +68 more
core +1 more source
Cytochrome b 5 Augments the 17,20-Lyase Activity of Human P450c17 without Direct Electron Transfer*
In the biosynthesis of steroid hormones, P450c17 is the single enzyme that catalyzes both the 17α-hydroxylation of 21-carbon steroids and the 17,20-lyase activity that cleaves the C17-C20 bond to produce C19sex steroids. Cytochrome b 5 augments the 17,20-
R. Auchus, Tim C. Lee, W. Miller
semanticscholar +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
Possible Application of Cytochrome b Gene for Human Identification
The mitochondrial cytochrome b gene (cytb) has been partially amplified and sequenced in order to identify the characteristic SNPs (single nucleotide polymorphism) for some Saudi Arabian tribes.
Sayed A.M. Amer +2 more
doaj +1 more source
Variasi Gen Mitokondria Cytochrome B Pada Dua Jenis Burung Kakatua Putih (Cacatua Alba Dan C. Moluccensis) [PDF]
Variation in The Mitochondrial Cytochrome b Gene in The Two White Cockatoo Species (Cacatua alba and C. molucensis). DNA sequence variation in the 791-bp of mitochondrial cytocrome b gene in the two white cockatoo species (C. alba and C.
Astuti, D. (Dwi)
core
A mutant of Neurospora crassa deficient in cytochrome c heme lyase activity cannot import cytochrome c into mitochondria [PDF]
The nuclear cyt-2-1 mutant of Neurospora crassa is characterized by a gross deficiency of cytochrome c (Bertrand, H., and Collins, R. A. (1978) Mol. Gen. Genet. 166, 1-13).
Drygas, Mariola E. +4 more
core +1 more source

