Results 91 to 100 of about 623,393 (330)

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Plasma Cytochrome c Detection Using a Highly Sensitive Electrochemiluminescence Enzyme-Linked Immunosorbent Assay

Biomarker Insights, 2017
Background: Cytochrome c is an intermembrane mitochondrial protein that is released to the bloodstream following mitochondrial injury. Methods and results: We developed an electrochemiluminescence immunoassay to measure cytochrome c in human and rat ...
Jeejabai Radhakrishnan, Rovi Origenes, Gina Littlejohn, Sanja Nikolich, Eunjung Choi, Sharon Smite, Lorissa Lamoureux, Alvin Baetiong, Manoj Shah, Raúl J Gazmuri   +9 more
doaj   +1 more source

Cytochrome C Biosensor—A Model for Gas Sensing

Sensors, 2011
This work is about gas biosensing with a cytochrome c biosensor. Emphasis is put on the analysis of the sensing process and a mathematical model to make predictions about the biosensor response.
Gabriele Nelles, Nadejda Krasteva, Ingeborg Hospach, Michael Hulko   +3 more
doaj   +1 more source

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

Effect of basic fibroblast growth factor and cytochrome c peroxidase combination in transgenic mice corneal epithelial healing process after excimer laser photoablation

Clinical Ophthalmology, 2011
Sergio Zaccaria Scalinci1, Lucia Scorolli1, Alessandro Meduri2, Pier Luigi Grenga3, Giulia Corradetti1, Cristian Metrangolo11Low Vision Center – University of Bologna, Bologna, Italy; 2Department of Surgical Specialities, Ophthalmology Clinic ...
Sergio Zaccaria Scalinci, Lucia Scorolli, Alessandro Meduri, et al   +3 more
doaj  

Early Decrease in Respiration and Uncoupling Event Independent of Cytochrome c Release in PC12 Cells Undergoing Apoptosis

International Journal of Cell Biology, 2012
Cytochrome c is a key molecule in mitochondria-mediated apoptosis. It also plays a pivotal role in cell respiration. The switch between these two functions occurs at the moment of its release from mitochondria.
Libera Berghella, Elisabetta Ferraro
doaj   +1 more source

Cytochrome c Peroxidase–Cytochrome c Complexes

, 2015
The yeast cytochrome c peroxidase (CCP)–cytochrome c (cytc) electron transfer system has been critically important in deciphering the molecular level details of protein–protein interactions and electron transfer. The crystal structure of the CCP–cytc together with a number mutagenesis, enzymological, and spectroscopic studies have provided a detailed ...
openaire   +3 more sources

Different Transport Pathways of Individual Precursor Proteins in Mitochondria [PDF]

, 1981
Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated ...
Allen E. H., Ambler R. P., Basile G., Conboy J. G., Cote C., Fisher W. R., Hackenberg H., Hallermayer G., Harmey M. A., Heller J., Jagow G., Korb H., Laemmli U. K., Lewin A., Maccechini M. -L., Maccechini M. -L., Michel R., Mihara K., Mori M., Nelson N, Paul K. G., Pelham H. R. B., Raymond Y., Schatz G., Schmelzer E., Sebald W., Shore G. S., Sonderegger P., Tzagoloff A., Zimmermann R., Zimmermann R., Zimmermann R.   +31 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Damage to proteins by peroxidized lipids

Journal of Lipid Research, 1963
The purpose of this research was to determine the mechanism of damage to protein by the free radical intermediates formed during the peroxidation of lipids. The reaction system consisted of linolenic acid, cytochrome c, and oxygen.
I.D. Desai, A.L. Tappel
doaj