Results 91 to 100 of about 20,306,851 (378)

Evolutionary Approaches to Study Cytochrome c Peroxidase

CHIMIA, 2001
Directed molecular evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies.
André Iffland, Petra Tafelmeyer, Susanne Gendreizig, Kai Johnsson   +3 more
doaj   +2 more sources

Thermodynamic Volume Cycles for Electron Transfer in the Cytochrome c Oxidase and for the Binding of Cytochrome c to Cytochrome c Oxidase [PDF]

Biophysical Journal, 1998
Dilatometry is a sensitive technique for measuring volume changes occurring during a chemical reaction. We applied it to the reduction-oxidation cycle of cytochrome c oxidase, and to the binding of cytochrome c to the oxidase. We measured the volume changes that occur during the interconversion of oxidase intermediates.
Gaston Hui Bon Hoa, Isabelle Rajotte, Peter C. Kahn, Mary Judith Kornblatt, Jack A. Kornblatt   +4 more
openaire   +3 more sources

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

Perturbation of Cytochrome c Maturation Reveals Adaptability of the Respiratory Chain in Mycobacterium tuberculosis

mBio, 2013
Mycobacterium tuberculosis depends on aerobic respiration for growth and utilizes an aa3-type cytochrome c oxidase for terminal electron transfer. Cytochrome c maturation in bacteria requires covalent attachment of heme to apocytochrome c, which occurs ...
Jennifer L. Small, Sae Woong Park, Bavesh D. Kana, Thomas R. Ioerger, James C. Sacchettini, Sabine Ehrt   +5 more
doaj   +1 more source

Import of cytochrome c into mitochondria [PDF]

, 1989
The covalent attachment of heme to apocytochrome c, and therefore the import of cytochrome c into mitochondria, is dependent on both NADH plus a cytosolic cofactor that has been identified to be FMN or FAD.
Neupert, Walter, Nicholson, Donald W.
core  

Evolution of the Couple Cytochrome c and Cytochrome c Oxidase in Primates [PDF]

, 2012
Mitochondrial energy metabolism has been affected by a broad set of ancient and recent evolutionary events. The oldest example is the endosymbiosis theory that led to mitochondria and a recently proposed example is adaptation to cold climate by anatomically modern human lineages.
Denis Pierron, Maik Hüttemann, Thierry Letellier, Derek E. Wildman, Lawrence I. Grossman   +4 more
openaire   +3 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

UV-light effects on cytochrome c modulated by the aggregation state of phenothiazines. [PDF]

PLoS ONE, 2013
The present study shows the factors that modulate the photodamage promoted by phenothiazines. Cytochrome c was irradiated with UV light for 120 min, over a pH range from 4.0 to 8.0, in the absence and in the presence of different concentrations of ...
Carolina G dos Santos, André L Silva, Flavio L Souza, Alexandre J C Lanfredi, Paolo Di Mascio, Otaciro R Nascimento, Tiago Rodrigues, Iseli L Nantes   +7 more
doaj   +1 more source

Different Transport Pathways of Individual Precursor Proteins in Mitochondria [PDF]

, 1981
Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated ...
Allen E. H., Ambler R. P., Basile G., Conboy J. G., Cote C., Fisher W. R., Hackenberg H., Hallermayer G., Harmey M. A., Heller J., Jagow G., Korb H., Laemmli U. K., Lewin A., Maccechini M. -L., Maccechini M. -L., Michel R., Mihara K., Mori M., Nelson N, Paul K. G., Pelham H. R. B., Raymond Y., Schatz G., Schmelzer E., Sebald W., Shore G. S., Sonderegger P., Tzagoloff A., Zimmermann R., Zimmermann R., Zimmermann R.   +31 more
core   +1 more source

Cell Membrane Vesicle Camouflaged Artificial Cells

Advanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres, Stefan Pendlmayr, Noga Gal, Cathrine Abild Meyer, Cecilie Ryberg, Olav Vestrheim, Noel Angelo Kalacas, Fatih Demir, Markus M. Rinschen, Karsten Haupt, Rajeshwar Prosad Mookerjee, Brigitte Städler   +11 more
wiley   +1 more source