Results 141 to 150 of about 40,950,057 (342)

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

open access: yesAdvanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li   +6 more
wiley   +1 more source

Barcoding animal life: cytochrome c oxidase subunit 1 divergences among closely related species

open access: yesProceedings of the Royal Society of London. Series B: Biological Sciences, 2003
P. Hebert, S. Ratnasingham, J. de Waard
semanticscholar   +1 more source

Cytochrome c and cytochrome oxidase in diaminobenzidine staining of mitochondria

open access: yes, 1974
Diaminobenzidine staining of mitochondrial cristae and inner membrane is decreased after extracting cytochrome c by freezing and thawing in NaCl; is enhanced by adding cytochrome c; is negative after staining under nitrogen.
Roels, Frank, F. ROELS
core   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin   +23 more
wiley   +1 more source

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

open access: yesCell, 1997
Peng Li   +6 more
semanticscholar   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

open access: yesAdvanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu   +12 more
wiley   +1 more source

Integration of the D‐Genome Reshapes Gene Transcription, Chromatin Architecture, and Metabolome of Allohexaploid Wheat, Leading to Enhanced Environmental Adaptability

open access: yesAdvanced Science, EarlyView.
Integration of the D‐genome reshapes gene transcription, chromatin architecture, and the metabolome of hexaploid wheat, leading to enhanced adaptability to salt, UV‐B, and alkali stress. ABSTRACT The hybridization‐led integration of the D‐genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally ...
Yanyan Liu   +23 more
wiley   +1 more source

Dimerization-induced conformational transitions of yeast iso-1 cytochrome c

open access: yesMagnetic Resonance Letters
Cytochrome c is a multifunctional protein involved in electron transport and apoptosis. However, its conformational landscape is complex and heterogeneous, which has obscured the functional understanding—particularly regarding its long-observed dimerized
Qianwen Wang   +13 more
doaj   +1 more source

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.

open access: yesCell, 1996
X. Liu   +4 more
semanticscholar   +1 more source

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