Prolonged linezolid therapy induces progressive mitochondrial dysfunction in human peripheral blood mononuclear cells. [PDF]
Martínez-Guitián M +11 more
europepmc +1 more source
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
Arab gum coating enhances the bioavailability and therapeutic potential of nanoselenium in cisplatin-induced testicular toxicity. [PDF]
Abdelbaset S +4 more
europepmc +1 more source
S11.11 FTIR detection of carboxyl groups in bovine heart cytochrome c oxidase
Amandine, Maréchal, Rich, Peter R.
openaire +1 more source
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang +7 more
wiley +1 more source
A soluble cytochrome containing c-type and a2-type haem groups from Micrococcus denitrificans [PDF]
openaire +2 more sources
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye +9 more
wiley +1 more source
Single-cell transcriptomics identifies ergothioneine as a mitochondrial protector to prevent AKI-to-CKD progression. [PDF]
Peng J, Chen J, Qian Z, Han M, Chen L.
europepmc +1 more source
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li +9 more
wiley +1 more source
Circulating Mitochondrial DNA Aggravates Post-Ischemic Functional and Metabolic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death. [PDF]
Sanz MN +5 more
europepmc +1 more source

