Results 91 to 100 of about 29,283 (148)

Proof of principle concept for the analysis and functional prediction of rare genetic variants in the CYP2C19 and CYP2D6 genes. [PDF]

Hum Genomics
Johansson I, Lu Y, Zhou Y, Krebs K, Akcan M, Milani L, Ingelman-Sundberg M.   +6 more
europepmc   +1 more source

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation. [PDF]

J Pharmacokinet Pharmacodyn
Pan X, Rowland Yeo K.
europepmc   +1 more source

Prevalence Estimates of Cytochrome P450 Phenoconversion in Youth Receiving Pharmacotherapy for Mental Health Conditions. [PDF]

Clin Pharmacol Ther
Gerlach S, Maruf AA, Shaheen SM, McCloud R, Heintz M, McAusland L, Arnold PD, Bousman CA.   +7 more
europepmc   +1 more source

Cytochrome P450 17 (CYP17), CYP2C19*2, CYP2C19*3 Gene Polymorphisms and Gastrointestinal Cancer Risk in Rural Maharashtra: A Hospital based Case-Control Study. [PDF]

Asian Pac J Cancer Prev
Datkhile KD, More AL, Patil MN, Gudur RA, Gudur AK.   +4 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P-Glycoprotein Inhibition. [PDF]

Clin Pharmacol Drug Dev
Jia H, Ballard TE, Zhang L, Cohen L, Bergagnini-Kolev MC, Templeton IE, Jones HM, Yin W.   +7 more
europepmc   +1 more source

The frequencies of CYP2C19*2, *3, and *17 alleles and their impact on the clinical efficacy of doubled maintenance dose of clopidogrel in Syrian patients with coronary artery disease. [PDF]

BMC Cardiovasc Disord
Haj Saleh N, A Youssef L.
europepmc   +1 more source

Identification and validation of Novel Estrogen Biosynthesis Biomarkers in Sinonasal Inverted Papilloma. [PDF]

Int J Med Sci
Yang YF, Yu SH, Liao JB, Lin YH.
europepmc   +1 more source

Drug-Drug Interaction Potential of Mavacamten with Midazolam: Combined Results from Clinical and Model-Based Studies. [PDF]

J Clin Pharmacol
Merali S, Sychterz C, Perera V, Gaohua L, Florea V, Murthy B.   +5 more
europepmc   +1 more source

A preliminary exploration of liver microsomes and PBPK to uncover the impact of CYP3A4/5 and CYP2C19 on tacrolimus and voriconazole drug-drug interactions. [PDF]

Sci Rep
Zhao YC, Zhang YK, Gao W, Liu HY, Xiao CL, Hou JJ, Li JK, Zhang BK, Xiang DX, Sandaradura I, Yan M.   +10 more
europepmc   +1 more source

Biological interactions of genotypes with , and in living donor liver transplantation recipients [PDF]

core   +1 more source