Results 111 to 120 of about 8,394 (135)

Integrative pharmacogenomics analysis predicts the platelet response in clopidogrel treated coronary artery disease (CAD) patients of South India. [PDF]

Sci Rep
Bharath G, Preethi L, Suriyam Nagappan A, Kalpana SR, Christopher R, Munirajan AK.   +5 more
europepmc   +1 more source

Development and Characterization of pFluor50, a Fluorogenic-Based Kinetic Assay System for High-Throughput Inhibition Screening and Characterization of Time-Dependent Inhibition and Inhibition Type for Six Human CYPs. [PDF]

Molecules
Shriwas P, Revnew A, Roo S, Bender A, Miller K, Hadad CM, Lane TR, Ekins S, McElroy CA.   +8 more
europepmc   +1 more source

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation. [PDF]

J Pharmacokinet Pharmacodyn
Pan X, Rowland Yeo K.
europepmc   +1 more source

Recurrent fexuprazan-induced liver injury following unintentional re-exposure. [PDF]

Br J Clin Pharmacol
Seong SJ, Kweon OS, Yoon YR, Kim YK, Kang YN, Jang SY.   +5 more
europepmc   +1 more source

Transcription factors of the Nuclear Factor I (NFI) family control hepatocyte differentiation and cytochrome P450 activity in human liver.

Pharmacol Res
Klein K, Burk O, Tremmel R, Buettner FA, Kaestle L, Schroth W, Muerdter TE, Eccles D, Schmidt AC, Nieß H, Zanger UM, Schwab M, Lauschke VM.   +12 more
europepmc   +1 more source

CYP2C19-Guided Voriconazole Therapy: A Precision Medicine Approach to Mitigate Adverse Effects in Japanese Patients. [PDF]

Clin Transl Sci
Katada Y, Hira D, Umemura K, Katsube Y, Ishimura H, Kojima Y, Hirai M, Kajiwara M, Sugimoto M, Endo H, Cao J, Ohta S, Kotani K, Hatazoe S, Tsuda M, Nakagawa S, Shinohara K, Tsuchido Y, Nagao M, Terada T.   +19 more
europepmc   +1 more source

Prevalence Estimates of Cytochrome P450 Phenoconversion in Youth Receiving Pharmacotherapy for Mental Health Conditions. [PDF]

Clin Pharmacol Ther
Gerlach S, Maruf AA, Shaheen SM, McCloud R, Heintz M, McAusland L, Arnold PD, Bousman CA.   +7 more
europepmc   +1 more source

Pharmacogenetics of steady-state metabolism, pharmacokinetics, and adverse effects of voriconazole in healthy participants. [PDF]

Drug Metab Dispos
Wu YP, Gelal A, Moon C, Metzger IF, Lu JBL, Callaghan JT, Skaar TC, Desta Z.   +7 more
europepmc   +1 more source

Proof of principle concept for the analysis and functional prediction of rare genetic variants in the CYP2C19 and CYP2D6 genes. [PDF]

Hum Genomics
Johansson I, Lu Y, Zhou Y, Krebs K, Akcan M, Milani L, Ingelman-Sundberg M.   +6 more
europepmc   +1 more source

Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants. [PDF]

Clin Pharmacol Ther
Ortega-Paz L, Thomas CD, Laudani C, Giordano S, Franchi F, Tunehag KR, Rollini F, Durukan S, Rossi JS, Farahmandsadr M, Stouffer GA, Been L, Keeley EC, Duarte JD, Beitelshees AL, Lee CR, Cavallari LH, Angiolillo DJ.   +17 more
europepmc   +1 more source