Interaktionen kardialer und antiretroviraler Medikation [PDF]
, 2018 Zusammenfassung: Neue therapeutische Optionen der hochaktiven antiretroviralen Therapie (HAART) haben die Morbidität und Mortalität von HIV-infizierten Patienten deutlich gesenkt, so dass nun vermehrt die altersspezifischen Erkrankungen manifest werden ...
Drewe, Jürgen, Egger, Sabin
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Eletriptan in the management of acute migraine. An update on the evidence for efficacy, safety, and consistent response [PDF]
, 2016 Migraine is a multifactorial, neurological and disabling disorder, also characterized by several autonomic symptoms. Triptans, selective serotonin 5-HT1B/1D agonists, are the first-line treatment option for moderate-to-severe headache attacks.
Capi, Matilde +6 more
core +1 more source
Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class [PDF]
, 2016 New psychoactive substances (NPS) are not tested for their cytochrome P450 (CYP) inhibition potential before consumption. Therefore, this potential was explored for tryptamine-derived NPS (TDNPS) including alpha-methyl tryptamines (AMTs), dimethyl ...
Brandt, SD +4 more
core +1 more source
Personalized prescribing: a new medical model for clinical implementation of psychotropic drugs. [PDF]
, 2016 The use of pharmacogenetic tests was already being proposed in psychiatry in the early 2000s because genetic factors were known to influence drug pharmacokinetics and pharmacodynamics.
Eap, C.B.
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Factors Influencing the Magnitude and Clinical Significance of Drug Interactions Between Azole Antifungals and Select Immunosuppressants [PDF]
, 2006 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90188/1/phco.26.12.1730 ...
Carver, Peggy L. +2 more
core +1 more source
Prevalence of cannabidiol use in persons with cystic fibrosis
Pediatric Pulmonology, Volume 59, Issue 12, Page 3790-3792, December 2024.
Emma M. Tillman +4 more
wiley +1 more source
Future of Pharmacogenetics in Cardiovascular Diseases [PDF]
, 2012 Introduction: Pharmacogenetics is the study of variations in DNA sequence as related to drug response (European Medicines Agency [EMA], 2007). Several gene-drug interactions have been discovered in the field of cardiovascular diseases (CVDs). These gene-
de Boer, A +7 more
core +2 more sources
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme [PDF]
, 2016 Cryptococcosis is a life-threatening disease often associated with HIV infection. Three Cryptococcus species CYP51 enzymes were purified and catalyzed the 14α-demethylation of lanosterol, eburicol, and obtusifoliol.
Garvey, Edward P. +8 more
core +1 more source
Clopidogrel Pharmacogenetics, resistance to antiplatelet therapy in ischemic stroke by Epigenome Wide Association Study (EWAS). [PDF]
, 2014 Curs 2012-2013Clopidogrel is a widely used antiplatelet drug used in preventing vascular events after suffering a first stoke. Genome-wide association studies (GWAS) has not been able to establish a clear association between polymorphisms and recurrence.
Gallego Fàbrega, Cristina
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