A study on the impact of CYP2C19 genotype and platelet reactivity assay on patients undergoing PCI [PDF]
BackgroundA thorough understanding of the patient's genotype and their functional response to a medication is necessary for improving event free survival.
Chidambaram, Sundar+9 more
core +2 more sources
Seguridad e interacciones de los Inhibidores de la Bomba de Protones (IBP) [PDF]
Los IBP han demostrado ser fármacos relativamente seguros después de muchos años de una amplia utilización. Las reacciones adversas con las que más frecuentemente se han asociado son leves y con escasa repercusión clínica.
Esplugues Mota, Juan Vicente
core
Enantiomers of methylenedioxy designer drugs : the role of cytochrome P450s and catechol-O-methyltransferase in their metabolism [PDF]
In the presented studies, the CYP dependent, enantioselective N-dealkylation and demethylenation of the designer drugs MDMA (Ecstasy), MBDB (Eden), and MDEA (Eve) was investigated.
Meyer, Markus Robert
core
Michael L. Lim+6 more
semanticscholar +1 more source
Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent [PDF]
Acimovic J+11 more
core +1 more source
Interaction of Modified Cyclodextrins with Cytochrome P-450
M. Ishikawa, H. Yoshii, T. Furuta
semanticscholar +1 more source
Cardiovascular Pharmacogenomics: Current Status and Future Directions—Report of a National Heart, Lung, and Blood Institute Working Group [PDF]
Boineau, Robin+10 more
core +2 more sources
Comparative in vitro assessment of CYP2C19 inhibition by ilaprazole and conventional proton pump inhibitors using a high throughput fluorometric assay. [PDF]
Priyadharshini A+4 more
europepmc +1 more source
Development and Characterization of pFluor50, a Fluorogenic-Based Kinetic Assay System for High-Throughput Inhibition Screening and Characterization of Time-Dependent Inhibition and Inhibition Type for Six Human CYPs. [PDF]
Shriwas P+8 more
europepmc +1 more source