Results 101 to 110 of about 9,195 (133)

Risk of opioid overdose associated with concurrent use of hydrocodone and CYP3A4-inhibiting calcium channel blockers: a population-based cohort study. [PDF]

Am J Epidemiol
Bea S, Basham CA, Edrees HH, Huybrechts KF, Vine SM, Glynn RJ, Bateman BT, Bykov K.   +7 more
europepmc   +1 more source

Physiologically-based pharmacokinetic model for predicting drug-drug interactions perpetrated by posaconazole in healthy subjects with normal weight and obesity: Concomitant use and washout. [PDF]

J Pharmacokinet Pharmacodyn
Bruno CD, Elmokadem A, Greenblatt DJ, Chow CR.   +3 more
europepmc   +1 more source

The neuroendocrine regulation of hepatic cytochrome P450 by N-methyl-D-aspartate receptors in the paraventricular and arcuate nuclei of the hypothalamus. [PDF]

Drug Metab Dispos
Pukło R, Bromek E, Basińska-Ziobroń A, Haduch A, Kuban W, Danek PJ, Daniel WA.   +6 more
europepmc   +1 more source

Impact of chrysosplenetin on the pharmacokinetics and anti-malarial efficacy of artemisinin against as well as in vitro CYP450 enzymatic activities in rat liver microsome [PDF]

core   +1 more source

Establishing a Quantitative Framework for Combined Oral Contraceptives: Evaluating the Impact of Drug-Drug Interactions on Exposure and Clinical (Surrogate) Efficacy Endpoints. [PDF]

J Clin Pharmacol
Chun D, Chen H, Cicali B, Guzy S, Hoechel J, Jiao T, Vozmediano V, Schmidt S.   +7 more
europepmc   +1 more source

In vitro and clinical data demonstrate negligible risk of drug-drug interactions with opelconazole, a novel inhaled antifungal agent. [PDF]

J Antimicrob Chemother
Cass LMR, Ayrton J, Brüggemann RJ, Moore J, Martin U, Grey L, Hyman M, Berman L.   +7 more
europepmc   +1 more source

A Population Pharmacokinetic Approach to Understand the Effect of Efavirenz on CYP3A Activity in Healthy Volunteers Using Midazolam as a Probe. [PDF]

CPT Pharmacometrics Syst Pharmacol
Collins KS, Aruldhas BW, Metzger IF, Lu JBL, Heathman MA, Quinney SK, Desta Z.   +6 more
europepmc   +1 more source

Sensitivity of Tepotinib to Inhibitors or Inducers of CYP3A4 and P-Gp: Drug Interaction Studies and Physiologically-Based Pharmacokinetic Analysis. [PDF]

Clin Transl Sci
Strotmann R, Lüpfert C, Krebs-Brown A, Ke A, Boedding M, Heuer J, Yeo KR, Benincosa L, Venkatakrishnan K.   +8 more
europepmc   +1 more source

Deciphering the Relative Contribution of CYP3A4 Versus P-Glycoprotein for the Shared Substrate Cyclosporine-Commentary on Lown et al. [PDF]

Clin Pharmacol Ther
Cascorbi I, Kim RB.
europepmc   +1 more source

Interaction of cytochrome P450 3A4 with the hydrophilic ligand tetraethylene glycol. [PDF]

Biochem Biophys Res Commun
Sevrioukova IF.
europepmc   +1 more source