Results 61 to 70 of about 9,123 (152)
European Journal of Clinical Pharmacology, 2022 Tung, Norint P., Ma, Joseph D.
openaire +2 more sources
Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa. [PDF]
, 2013 Cytochrome P450 3A5 (CYP3A5) is an enzyme involved in the metabolism of many therapeutic drugs. CYP3A5 expression levels vary between individuals and populations, and this contributes to adverse clinical outcomes.
Bains, RK +6 more
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Individualization of Immunosuppressive Therapy after Solid Organ Transplantation [PDF]
, 2014 __Abstract__ When an individual’s kidneys fail, there are three treatment options: hemodialysis, peritoneal dialysis or kidney transplantation. A successful kidney transplantation results in the best patient survival and a better quality of life ...
Bouamar, R. (Rachida)
core +1 more source
Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]
, 1994 Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L. +2 more
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Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers [PDF]
, 2018 Background: Benzimidazoles are often used concomitantly with protease inhibitors in patients with helminthic disease and HIV infection. Low bioavailability and extensive first-pass metabolism make benzimidazoles prone to pharmacokinetic drug interactions.
Corti, Natascia +6 more
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Polymorphic drug metabolising enzymes:Assessment of activities by phenotyping and genotyping in clinical pharmacology [PDF]
, 2001 Drug effects (pharmacodynamics) are determined by drug concentration at target site and the affinity of the drug for a target. Pharmacogenetics describes inherited differences in drug metabolising enzyme activities and differences in drug transporters ...
Tamminga, Willem Jan
core +2 more sources
Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]
, 2014 To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat +2 more
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