Results 81 to 90 of about 9,123 (152)

Genotype-Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers. [PDF]

Clin Transl Sci
Etkins J, So GC, Lu JBL, Koyama S, Gisch DL, Melo Ferreira R, Cheng YH, McClara K, Jun J, Miller M, Desta Z, Eadon MT.   +11 more
europepmc   +1 more source

Application of Physiologically-Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4-Mediated Pirtobrutinib-Drug Interactions. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tian DD, Hall SD, Chapman SC, Posada MM.
europepmc   +1 more source

The Pivotal Role of GR-CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood. [PDF]

Adv Sci (Weinh)
Sun X, Liu J, Xiang E, Li X, Yan X, Wang Y, Li F, Kou H, Wang H, Guo Y.   +9 more
europepmc   +1 more source

Effect of Testosterone Therapy on Cytochrome P450 3A and P-Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults. [PDF]

Pharmacotherapy
Hunter M, Coig R, Risler L, Patton KK, Narla RR, Greene DN, Burke AK, Micks E, Hebert MF, Cirrincione LR.   +9 more
europepmc   +1 more source

Outcomes following exposure to drug interactions with ibrutinib in patients with chronic lymphocytic leukaemia. [PDF]

Br J Haematol
Hoang T, Cheung MC, Juurlink DN, Chan KKW, Lau C, Liu N, Abdel-Qadir H, Prica A, Hay AE, Vijenthira A, Mozessohn L.   +10 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling in Patients With Hepatic Impairment: Are Changes in Bosutinib Exposure Profiles Driven by Altered Absorption or Distribution? [PDF]

CPT Pharmacometrics Syst Pharmacol
Muto C, Jones HM, Yamazaki S.
europepmc   +1 more source

Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity. [PDF]

Front Pharmacol
Fashe MM, Lee J, Grieco JT, Fallon JK, Mulrenin IR, Gower MN, Jackson KD, Boggess KA, Lee CR.   +8 more
europepmc   +1 more source

Effect of Rifampicin on the Pharmacokinetics of Valemetostat and Its Primary Metabolite: A Phase 1 Study in Healthy Participants. [PDF]

Clin Transl Sci
Tachibana M, Matsuki S, Kurata A, Fukae M, Shinohara S, Shimizu T.   +5 more
europepmc   +1 more source

In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]

Bull Math Biol
Kahiya ET, Smutný T, Smutná L, Duintjer Tebbens J, Pávek P, Bernhauerová V.   +5 more
europepmc   +1 more source

Comparative Analysis of Isavuconazole DDIs With Other Azole Antifungal Drugs and PBPK Model-Informed Dosing Recommendations for Anticancer Drugs. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goosen TC, Wu X, Lin J, Cheruvu N, Raber SR, de Figueiredo MLN, Varma MVS.   +6 more
europepmc   +1 more source