Results 111 to 120 of about 778,835 (257)

Enzyme as Maxwell's Demon: Steady-state Deviation from Chemical Equilibrium by Enhanced Enzyme Diffusion [PDF]

open access: yesarXiv
Enhanced enzyme diffusion (EED), in which the diffusion coefficient of an enzyme transiently increases during catalysis, has been extensively reported experimentally. We numerically and analytically demonstrate that such enzymes can act as Maxwell's demons.
arxiv  

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Aerobic exercise improves astrocyte mitochondrial quality and transfer to neurons in a mouse model of Alzheimer's disease

open access: yesBrain Pathology, Volume 35, Issue 3, May 2025.
Aerobic exercise improves transfer of healthy mitochondria from astrocytes to neurons in the 5 × FAD mice. Abstract Mitochondrial dysfunction is a well‐established hallmark of Alzheimer's disease (AD). Despite recent documentation of transcellular mitochondrial transfer, its role in the pathogenesis of AD remains unclear.
Jiachen Cai   +10 more
wiley   +1 more source

Ergosterol‐induced immune response in barley involves phosphorylation of phosphatidylinositol phosphate metabolic enzymes and activation of diterpene biosynthesis

open access: yesNew Phytologist, Volume 246, Issue 3, Page 1236-1255, May 2025.
Summary Lipids play crucial roles in plant–microbe interactions, functioning as structural components, signaling molecules, and microbe‐associated molecular patterns (MAMPs). However, the mechanisms underlying lipid perception and signaling in plants remain largely unknown. Here, we investigate the immune responses activated in barley (Hordeum vulgare)
Pia Saake   +11 more
wiley   +1 more source

ReactZyme: A Benchmark for Enzyme-Reaction Prediction [PDF]

open access: yes38th Conference on Neural Information Processing Systems (NeurIPS 2024) Track on Datasets and Benchmarks
Enzymes, with their specific catalyzed reactions, are necessary for all aspects of life, enabling diverse biological processes and adaptations. Predicting enzyme functions is essential for understanding biological pathways, guiding drug development, enhancing bioproduct yields, and facilitating evolutionary studies. Addressing the inherent complexities,
arxiv  

Axial Ligand Lability and Coordination Induced Spin State Variations of Tetracarbene Iron(II) Thiolato Complexes

open access: yesEuropean Journal of Inorganic Chemistry, Volume 28, Issue 11, April 9, 2025.
A series of newly synthesized iron(II) thiolato complexes based on two different macrocyclic tetracarbene ligands shows coordination induced spin state variations from low‐spin to intermediate spin states as well as ligand lability leading to a temperature‐dependent equilibrium between the penta‐ and six‐coordinate species and axial ligand scrambling ...
Isabelle Becker   +6 more
wiley   +1 more source

Induction of Aryl Hydrocarbon Hydroxylase in Ambystoma tigrinum [PDF]

open access: yes, 1974
Aryl hydrocarbon hydroxylase (AHH) was induced 15-fold in Ambystoma tigrinum by intraperitoneal injection of 3-methylcholanthrene in corn oil, or 10-fold by addition of aromatic polycyclic hydrocarbons to the aqueous environment of the neotene animal ...
Colvin, David P.
core  

Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages

open access: yesAdvanced Therapeutics, Volume 8, Issue 4, April 2025.
Tackling the problem of tuberculosis (TB) and human immunodeficiency virus (HIV) co‐infection is a serious global health concern affecting people of all ages. This review presents the characteristics of both diseases, current treatment and diagnostic guidelines, associated problems, innovations in disease management, and overall effects on global ...
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
wiley   +1 more source

Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
An engineered Escherichia coli is developed to efficiently produce adipic acid (AA) from cyclohexanol, KA oil (a mixture of cyclohexanol and cyclohexanone), or cyclohexane through a combination of enzyme screening, protein fusion, and genome editing techniques. This approach has achieved the highest recorded productivity for biological AA production to
Fei Wang   +6 more
wiley   +1 more source

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