Results 131 to 140 of about 35,768 (229)

Cytochrome P450_BM-3 and P450 11A1 retain Compound I (FeO³⁺) chemistry with electrophilic substrates poised for Compound 0 (Fe³⁺O₂^-) reactions. [PDF]

J Biol Chem
McCarty KD, Tateishi Y, Guengerich FP.
europepmc   +1 more source

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation. [PDF]

J Pharmacokinet Pharmacodyn
Pan X, Rowland Yeo K.
europepmc   +1 more source

<i>Boswellia carteri</i> Birdw. Resin Extract Induces Phase-I Cytochrome P-450 Enzyme Gene Expressions in Human Hepatocarcinoma (Hep G2) Cells: In vitro and in silico Studies. [PDF]

Biologics
Alghamdi SS, Albahlal HN, Alajmi RS, Alsharidah A, Almogren A, Suliman R, Alehaideb ZI.   +6 more
europepmc   +1 more source

Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes. [PDF]

Int J Mol Sci
Sakamuru S, Travers J, Klumpp-Thomas C, Huang R, Witt KL, Ferguson SS, Simmons SO, Reif DM, Simeonov A, Xia M.   +9 more
europepmc   +1 more source

Cloning, heterologous expression, and expression analysis of SinSyn7 gene from Sinomenium acutum. [PDF]

PLoS One
Chen J, Chen X, Zhang L, Huang S, Chen X, Huang X, Yang H.   +6 more
europepmc   +1 more source

Temporal changes of hepatic drug-metabolizing enzymes mediated by hepatic ischemia-reperfusion injury and the protective effect of Oridonin. [PDF]

Sci Rep
Gu T, Dai F, Cai M, Zhang X, Xie D, Jiang H, Tian L, Yan L, Lan W, Lv H, Tang L, Li H, Liu Z.   +12 more
europepmc   +1 more source

Overexpression of cytochrome P450 and esterase genes in pyrethroid-resistant wild Culex quinquefasciatus populations from sub-Himalayan West Bengal, India. [PDF]

Parasitol Res
Saha A, Das P, Das S, Saha D.
europepmc   +1 more source

The Immature Infant Liver: Cytochrome P450 Enzymes and their Relevance to Vaccine Safety and SIDS Research. [PDF]

Int J Med Sci
Goldman GS, Cheng RZ.
europepmc   +1 more source

P450 Biarylitide Synthase ShyB Catalyzes the Cross-Link Between His-C2 and Tyr-O4 on the Precursor Peptide. [PDF]

Org Lett
Khan AH, Haedar JR, Kiselov V, Romanuks V, Smits G, Donadio S, Phan CS.   +6 more
europepmc   +1 more source

Effect of Rifampicin on the Pharmacokinetics of Valemetostat and Its Primary Metabolite: A Phase 1 Study in Healthy Participants. [PDF]

Clin Transl Sci
Tachibana M, Matsuki S, Kurata A, Fukae M, Shinohara S, Shimizu T.   +5 more
europepmc   +1 more source