Results 101 to 110 of about 297,833 (301)

Inhibition of Cytochrome P450 2E1, Cytochrome P450 3A6 and Cytochrome P450 2A6 by Citrus Essential Oils [PDF]

, 2010
Cytochrome P450 enzymes in the liver catalyze reactions involving the reduction of molecular oxygen and the oxidation of organic substrates. In some cases the resulting products may have the potential to contribute to oxidative stress within this organ ...
Williamson, Emily Ann, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation [PDF]

, 2011
Background Cytochrome-P450 (CYP450) epoxygenases metabolise arachidonic acid (AA) into four different biologically active epoxyeicosatrienoic acid (EET) regioisomers.
Geisslinger, Gerd, Gerd Geisslinger, Brandes, Ralf P., Brandes, Ralf, Michael J Fischer, Fleming, Ingrid, Scholich, Klaus, Woolf Clifford J, Ralf P Brandes, Clifford J Woolf, Fleming Ingrid, Reeh, Peter Werner, Brenneis Christian, Fischer, Michael, Coste Ovidiu, Coste, Ovidiu, Brandes Ralf P, Kai Altenrath, Reeh Peter W, Christian Brenneis, Scholich Klaus, Sisignano, Marco, Reeh, Peter W., Altenrath Kai, Ingrid Fleming, Peter W Reeh, Woolf, Clifford J., Angioni Carlo, Geisslinger Gerd, Angioni, Carlo Federico, Klaus Scholich, Brenneis, Christian, Ovidiu Coste, Carlo Angioni, Sisignano Marco, Marco Sisignano, Fischer, Michael J., Fischer Michael J, Altenrath, Kai, Angioni, Carlo   +39 more
core   +3 more sources

Expression of CYP71B7, a cytochrome P450 expressed sequence tag from Arabidopsis thaliana

, 1997
The systematic sequencing of anonymous cDNA clones (expressed sequence tags or ESTs) from the plantArabidopsis thalianahas identified a number of cDNAs with similarity to known cytochrome P450 sequences.
Hallahan, D. L., Maughan, J. A., Nugent, J. H. A.   +2 more
core   +1 more source

The cytochrome P450 gene GhCYP94C1 is involved in drought stress in upland cotton (Gossypium hirsutum L.)

, 2023
Cytochrome P450 proteins belong to one of the largest families of enzyme proteins in plants and play important roles in plant growth and development and the stress response. In our previous studies, a cytochrome P450 gene, GhCYP94C1 (cytochrome P450 94C1)
Lijiao Gu, Shuxun Yu, Pengyun Chen
core   +1 more source

Successful treatment of schizophrenia with melperone augmentation in a patient with phenotypic CYP2D6 ultrarapid metabolization: a case report

Journal of Medical Case Reports, 2012
Introduction There are limited treatment options for people with schizophrenia with cytochrome P450 2D6 ultrarapid metabolizer status who do not respond to amisulpride.
Gahr Maximilian, Gastl Regina, Kölle Markus A, Schönfeldt-Lecuona Carlos, Freudenmann Roland W   +4 more
doaj   +1 more source

In Silico Screening of Plant-Derived Termiticidal Compounds Targeting Cytochrome P450 in Coptotermes spp. (Blattodea: Rhinotermitidae) for Sustainable Termite Management

Plants
Termites of the genus Coptotermes are among the most destructive structural pests worldwide, owing to their efficient lignocellulose degradation and metabolic adaptability mediated in part by cytochrome P450 enzymes. Although numerous botanical compounds
Deepak Kumar Mahanta, Tanmaya Kumar Bhoi, Sumit Jangra   +2 more
doaj   +1 more source

Ergosterol promotes the atypical kinetics of cytochrome P450 reductase and cytochrome P450-3A4 in recombinant yeast system

, 2007
Atypical kinetics of cytochrome P450 enzyme confounds the accurate prediction of drug metabolism from in vitro to in vivo in cDNA-expressed system. Microsomal membrane is reported to be a potential factor to modulate the cytochrome P450 (CYP) kinetics in
程婕, 刘勇, 杨凌
core  

Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans

, 2011
To identify and characterize cytochrome P450 enzymes (CYPs) responsible for the metabolism of racemic ketamine in 3 mammalian species in vitro by use of chemical inhibitors and ...
Meike Mevissen, Mevissen, Meike, Thormann, Wolfgang, Regula Theurillat, Theurillat, Regula, Andrea Schmitz, Wolfgang Thormann, Mössner, Lone D, Schmitz, Andrea, Lone D. Mössner   +9 more
core   +1 more source

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]

, 2009
Autoimmune hepatitis (AIH) is a chronic liver disease of unknown etiology, characterized by a loss of tolerance against hepatocytes leading to the progressive destruction of hepatic parenchyma and cirrhosis. Clinical signs for AIH are interface hepatitis
Holdener, Martin
core  

First Evidence for Ozonido‐TMC Complexes of Iron and Cobalt

Angewandte Chemie International Edition, EarlyView.
Reaction of ozone with iron(II) complexes [(TMC)Fe(OTf)]BArF, [(D12‐TMC)Fe(OTf)]BArF, and cobalt(II) complexes [(TMC)Co(OTf)]BArF, [(D12‐TMC)Co(X)]BArF (X = OTf, F) gives ozonido and oxido complexes at temperatures as low as –155°C in a 4:1 mixture of 2‐Me‐THF and THF. ABSTRACT We present compelling evidence for the first Fe‐ and Co‐ozonido complexes: [
Stefan Schaub, Dennis Gerbig, Raffael C. Wende, Heike Hausmann, Jonathan Becker, Christian Würtele, Laura Senft, Ina Kellner, Gunasekaran Velmurugan, Marion Kerscher, Ivana Ivanović‐Burmazović, Peter Comba, Joshua Telser, Peter R. Schreiner, Siegfried Schindler   +14 more
wiley   +1 more source