Results 141 to 150 of about 506,903 (380)
Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis
Nature Chemical Biology, 2020 Y. Zou +9 more
semanticscholar +1 more source
Cytochromes P450: a success story.
Genome biology, 2000 Cytochrome P450 proteins, named for the absorption band at 450 nm of their carbon-monoxide-bound form, are one of the largest superfamilies of enzyme proteins. The P450 genes (also called CYP) are found in the genomes of virtually all organisms, but their number has exploded in plants.
Werck-Reichhart, D., Feyereisen, René
openaire +5 more sources
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
Journal of Integrative Agriculture, 2016 The red imported fire ant (Solenopsis invicta) is a global major invasive pest, and has caused significant economic, social and environmental impacts since its invasion to mainland of China in 2004.
Bai-zhong ZHANG +5 more
doaj
Bulletin of the National Research Centre, 2018 Background Insulin-producing cells differentiated from human mesenchymal stem cells demonstrate limited glucose-stimulated insulin secretion. Cytochrome P450 2J2 and its product epoxyeicosatrienoic acids regulate β-cell function in the human pancreas ...
Loaa A. Tag Eldeen +2 more
doaj +1 more source
Effect of hemochromatosis on hepatic cytochrome P450 and antipyrine metabolism in humans. [PDF]
, 1984 Herbert L. Bonkovsky +2 more
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Cancer Communications, EarlyView.Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu +16 more
wiley +1 more source
The Effects of Phenobarbital or Cholic Acid on Hepatic Microsomal Cytochrome P450 and Hydroxylation of 2-AAF in Cholestatic Rats [PDF]
, 1981 B.H. Kim, Ye-Seon Hong, N.E. Sung
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Chemistry &Biodiversity, EarlyView.ABSTRACT Benzodiazepines are widely used in the treatment of anxiety, but their use may be interrupted due to side effects. This study evaluated the indole alkaloids isocarapanaubine (indole alkaloid 1 [AIN1]) and 18‐β‐hydroxy‐3‐epi‐α‐yohimbine (indole alkaloid 2 [AIN2]), extracted from Rauvolfia ligustrina, in adult zebrafish.
Nádia Aguiar Portela Pinheiro +10 more
wiley +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Chemistry &Biodiversity, EarlyView.ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos +8 more
wiley +1 more source