The study was performed to investigate the effects of the separate and combined action of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and vitamin D3 on the activity of the components of the oxygenase and reductase chains of the monooxygenase system ...
I. O. Shymanskyi +3 more
doaj +2 more sources
Development of a new platform technology for plant Cytochrome P450 fusions [PDF]
To date more than 15000 Cytochromes P450 have been identified and named so far, with one third belonging to the plant kingdom. This is a key biochemical resource, providing a wealth of biocatalysts covering a diverse range of chemistries ...
Schückel, Julia
core +6 more sources
Cytochromes P450 in Nanodiscs [PDF]
Nanodiscs have proven to be a versatile tool for the study all types of membrane proteins, including receptors, transporters, enzymes and viral antigens. The self-assembled Nanodisc system provides a robust and common means for rendering these targets soluble in aqueous media while providing a native like bilayer environment that maintains functional ...
Ilia G, Denisov, Stephen G, Sligar
openaire +2 more sources
Cytochrome P450 metabolism mediates low‐temperature resistance in pinewood nematode
Pinewood nematode (PWN; Bursaphelenchus xylophilus) is a devastating invasive species that is expanding into colder regions. Here, we investigated the molecular mechanisms underlying low‐temperature resistance of PWN.
Bowen Wang +6 more
doaj +1 more source
An Exploration of the Sub-Register of Chemical Engineering Research Papers Published in English
The increased pressures for high-volume, high-impact publications in English language and the high rejection rates of submitted manuscripts for publications present an often unsurpassable obstacle for (early career) researchers.
Myrto-Panagiota Zacharof +1 more
doaj +1 more source
Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions [PDF]
Pyrethroid insecticides are used to control diseases spread by arthropods. We have developed a suite of pyrethroid mimetic activity-based probes (PyABPs) to selectively label and identify P450s associated with pyrethroid metabolism.
O'Neill, Paul +18 more
core +1 more source
Methods for determining Cytochrome P450 reductase in biological fluids of animals [PDF]
The study provides a literature review of modern methods for determining Cytochrome P450 reductase. The importance of the enzyme in the body is established.
Ponamarev Vladimir
doaj +1 more source
Cloning and Expression of Multiple Cytochrome P450 Genes: Induction by Fipronil in Workers of the Red Imported Fire Ant (Solenopsis invicta Buren). [PDF]
Both exogenous and endogenous compounds can induce the expression of cytochrome P450 genes. The insect cytochrome P450 genes related to insecticide resistance are likely to be expressed as the "first line of defense" when challenged with insecticides. In
Baizhong Zhang +4 more
doaj +1 more source
Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]
Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun +23 more
core +1 more source
Cytochrome P450 monooxygenases
The field of P450 research is progressing rapidly. The active sites of structurally characterized bacterial P450 enzymes have been rationally re-engineered to alter both substrate specificity and selectivity of substrate oxidation. Many human P450 enzymes have been functionally expressed and new methods of substrate turnover described.
HALKIER BARBARA ANN +3 more
openaire +6 more sources

