Results 21 to 30 of about 7,052 (211)

Liver cytochrome P450-hydroxylation system of tumor-bearing rats under the influence of ?-3 polyunsaturated fatty acids and vitamin D(3)

open access: yesThe Ukrainian Biochemical Journal, 2018
The study was performed to investigate the effects of the separate and combined action of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and vitamin D3 on the activity of the components of the oxygenase and reductase chains of the monooxygenase system ...
I. O. Shymanskyi   +3 more
doaj   +1 more source

Cytochrome P450 flexibility [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Cytochrome P450 refers to a group of enzymes that catalyze the monooxygenation of various organic molecules in the following reaction: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} \begin ...
openaire   +2 more sources

Cytochrome P450 2S1 is Reduced by NADPH-Cytochrome P450 Reductase [PDF]

open access: yesDrug Metabolism and Disposition, 2011
Cytochrome P450 (P450) 2S1 is one of the orphan P450s without a clear physiological function. Controversy has arisen as to whether it can interact with NADPH-P450 reductase and accept electrons. The reduction of 1,4-bis{[2-(dimethylamino-N-oxide)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione (AQ4N) by P450 2S1 was confirmed, and the NADPH consumption ...
Yi, Xiao   +2 more
openaire   +2 more sources

Identification and expression profile of the soil moisture and Ralstonia solanacearum response CYPome in ginger (Zingiber officinale) [PDF]

open access: yesPeerJ, 2021
Background Cytochrome P450s play crucial roles in various biosynthetic reactions. Ginger (Zingiber officinale), which is often threatened by Ralstonia solanacearum, is the most economically important crop in the family Zingiberaceae.
Mengjun Huang   +5 more
doaj   +2 more sources

The catalytic function of cytochrome P450 is entwined with its membrane-bound nature [version 1; referees: 4 approved]

open access: yesF1000Research, 2017
Cytochrome P450, a family of monooxygenase enzymes, is organized as a catalytic metabolon, which requires enzymatic partners as well as environmental factors that tune its complex dynamic.
Carlo Barnaba   +3 more
doaj   +1 more source

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

open access: yesmBio, 2020
Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms
Jeffrey M. Rybak   +12 more
doaj   +1 more source

The Role of procollagen type 1 amino-terminal propertied (P1NP) Cytochrome P450 (CYPs) and Osteoprotegerin (OPG) as Potential Bone function markers in Prostate Cancer Bone Metastasis

open access: yesRomanian Journal of Laboratory Medicine, 2023
Background: Procollagen type I amino-terminal propeptide (PINP) is often present during osteoblast development and could be a biomarker of early bone development. Osteoprotegerin (OPG) may protect tumor cells from apoptosis.
Yousif Pshtiwan A.   +1 more
doaj   +1 more source

Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells

open access: yesScientific Reports, 2018
The COS-7 (CV-1 in Origin with SV40 genes) cells are known as non-steroidogenic cells because they are derived from kidney cells and the kidney is defined as a non-steroidogenic organ.
Mitsuki Nozaki   +9 more
doaj   +1 more source

Antioxidant Activities of Celery and Parsley Juices in Rats Treated with Doxorubicin

open access: yesMolecules, 2010
We have examined the influence of diluted pure celery and parsley leaf and root juices and their combinations with doxorubicin on the antioxidant status [as measured by the content of reduced glutathione (GSH) and ferric reducing antioxidant power (FRAP)]
Svetlana Trivic   +4 more
doaj   +1 more source

The interplay between tubulins and P450 cytochromes during Plasmodium berghei invasion of Anopheles gambiae midgut. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Plasmodium infection increases the oxidative stress inside the mosquito, leading to a significant alteration on transcription of Anopheles gambiae detoxification genes.
Rute C Félix, Henrique Silveira
doaj   +1 more source

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