Results 31 to 40 of about 283,519 (305)

Cytochrome P450 flexibility [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Cytochrome P450 refers to a group of enzymes that catalyze the monooxygenation of various organic molecules in the following reaction: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} \begin ...
openaire   +2 more sources

Cytochrome P450 2S1 is Reduced by NADPH-Cytochrome P450 Reductase [PDF]

open access: yesDrug Metabolism and Disposition, 2011
Cytochrome P450 (P450) 2S1 is one of the orphan P450s without a clear physiological function. Controversy has arisen as to whether it can interact with NADPH-P450 reductase and accept electrons. The reduction of 1,4-bis{[2-(dimethylamino-N-oxide)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione (AQ4N) by P450 2S1 was confirmed, and the NADPH consumption ...
Yi, Xiao   +2 more
openaire   +2 more sources

Identification and expression profile of the soil moisture and Ralstonia solanacearum response CYPome in ginger (Zingiber officinale) [PDF]

open access: yesPeerJ, 2021
Background Cytochrome P450s play crucial roles in various biosynthetic reactions. Ginger (Zingiber officinale), which is often threatened by Ralstonia solanacearum, is the most economically important crop in the family Zingiberaceae.
Mengjun Huang   +5 more
doaj   +2 more sources

Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]

open access: yes, 2017
BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de   +5 more
core   +1 more source

The catalytic function of cytochrome P450 is entwined with its membrane-bound nature [version 1; referees: 4 approved]

open access: yesF1000Research, 2017
Cytochrome P450, a family of monooxygenase enzymes, is organized as a catalytic metabolon, which requires enzymatic partners as well as environmental factors that tune its complex dynamic.
Carlo Barnaba   +3 more
doaj   +1 more source

Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202 [PDF]

open access: yes, 2018
CYP17A1 is a key steroidogenic enzyme known to conduct several distinct chemical transformations on multiple substrates. In its hydroxylase activity, this enzyme adds a hydroxyl group at the 17α position of both pregnenolone and progesterone at ...
Bangcharoenpaurpong O.   +8 more
core   +2 more sources

The Role of procollagen type 1 amino-terminal propertied (P1NP) Cytochrome P450 (CYPs) and Osteoprotegerin (OPG) as Potential Bone function markers in Prostate Cancer Bone Metastasis

open access: yesRomanian Journal of Laboratory Medicine, 2023
Background: Procollagen type I amino-terminal propeptide (PINP) is often present during osteoblast development and could be a biomarker of early bone development. Osteoprotegerin (OPG) may protect tumor cells from apoptosis.
Yousif Pshtiwan A.   +1 more
doaj   +1 more source

CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana [PDF]

open access: yes, 2012
Infection of insects by the entomopathogenic fungus Beauveria bassiana proceeds via attachment and penetration of the host cuticle. The outermost epicuticular layer or waxy layer of the insect represents a structure rich in lipids including abundant ...
Bernard, Grausem   +6 more
core   +2 more sources

Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells

open access: yesScientific Reports, 2018
The COS-7 (CV-1 in Origin with SV40 genes) cells are known as non-steroidogenic cells because they are derived from kidney cells and the kidney is defined as a non-steroidogenic organ.
Mitsuki Nozaki   +9 more
doaj   +1 more source

Antioxidant Activities of Celery and Parsley Juices in Rats Treated with Doxorubicin

open access: yesMolecules, 2010
We have examined the influence of diluted pure celery and parsley leaf and root juices and their combinations with doxorubicin on the antioxidant status [as measured by the content of reduced glutathione (GSH) and ferric reducing antioxidant power (FRAP)]
Svetlana Trivic   +4 more
doaj   +1 more source

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