Results 221 to 230 of about 506,903 (380)

Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives [PDF]

, 1999
Magang Shou, Mei Qin, JR. Michael W. ETTORE, Renke Dai, Thomas A. Baillie, Thomas H. Rushmore   +5 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Cannabinoids and the endocannabinoid system in the regulation of cytochrome P450 metabolic activity-a review. [PDF]

Front Pharmacol
Fonseca CDF, Zendulka O, Juřica J.
europepmc   +1 more source

Identification of fatty acid hydroperoxide cofactors in the cytochrome P450-mediated oxidation of estrogens to quinone metabolites. Role and balance of lipid peroxides during estrogen-induced carcinogenesis.

, 1994
Mindy Wang, J G Liehr
openalex   +1 more source

Brassinosteroids Rescue the Deficiency of CYP90, a Cytochrome P450, Controlling Cell Elongation and De-etiolation in Arabidopsis [PDF]

, 1996
Miklós Szekeres, Kinga Németh, Zsuzsanna Koncz–Kálmán, Jaideep Mathur, Annette Kauschmann, Thomas Altmann, George P. Rédei, Ferenc Nagy, Jeff Schell, Csaba Koncz   +9 more
openalex   +1 more source

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Pharmacological Reviews, 2016
J. Backman, Anne M. Filppula, M. Niemi, P. Neuvonen   +3 more
semanticscholar   +1 more source

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

International Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville, Lisa J. Russell, Kay Padget, Akram Ghantous, Jessica Nordlund, Jill A. McKay   +5 more
wiley   +1 more source

Function of cytochrome P450 CYP72A1182 in metabolic herbicide resistance evolution in Amaranthus palmeri populations. [PDF]

J Exp Bot
Rigon CAG, Küpper A, Sparks C, Montgomery J, Peter F, Schepp S, Perez-Jones A, Tranel PJ, Beffa R, Dayan FE, Gaines TA.   +10 more
europepmc   +1 more source

Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

, 1993
Mala Mahendroo, Carole R. Mendelson, E R Simpson   +2 more
openalex   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source