Results 251 to 260 of about 506,903 (380)

Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons. [PDF]

J Med Chem
Kundu D, Franchini L, Hasdemir HS, Lloyd E, Maturano J, Rabl K, Denissiouk AN, Schumacher M, Sarlah D, Hellman J, Tajkhorshid E, Orlandi C, Das A.   +12 more
europepmc   +1 more source

Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera. [PDF]

, 1996
Marie Robin, Michel Maratrat, Marie Le Roy, Frédéric Breton, Eric Bonierbale, Patrick M. Dansette, F. Ballet, Daniel Mansuy, Dominique Pessayre   +8 more
openalex   +1 more source

CYP2C19 Loss‐of‐Function Is an Independent Risk Factor of Coronary Artery Disease in Patients With Hypertension

Journal of Clinical Laboratory Analysis, EarlyView.
The relationship between Cytochrome P450 2C19 (CYP2C19) polymorphisms and coronary artery disease (CAD) in hypertensive patients was analyzed. CYP2C19 loss‐of‐function, BMI ≥ 24.0 kg/m2, and history of alcoholism were independent risk factors for CAD in hypertensive patients.
Guoliang Wei, Bin Li, Hao Wang, Wenhao Chen, Kehui Chen, Weihong Wang, Shen Wang, Hui Zeng, Yuanliang Liu, Yue Zeng, Hui Rao   +10 more
wiley   +1 more source

Toxic Effects of p-Chloroaniline on Cells of Fungus <i>Isaria fumosorosea</i> SP535 and the Role of Cytochrome P450. [PDF]

Toxics
Huang S, Gao J, Zhou L, Gao L, Song M, Zeng Q.   +5 more
europepmc   +1 more source

Structure-function relationships of membrane-bound heme-enzyme, cytochrome P450.

, 1992
Tôru Shimizu
openalex   +2 more sources

The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum [PDF]

, 1995
Elzbieta Szczesna-Skorupa, Kwangseog Ahn, Ci-Di Chen, Balraj Doray, Byron Kemper   +4 more
openalex   +1 more source

Recent Structural Insights into Cytochrome P450 Function.

TIPS - Trends in Pharmacological Sciences, 2016
F. Guengerich, M. Waterman, M. Egli
semanticscholar   +1 more source

A Physiologically Based Modeling Approach to Evaluate Intravenous Levetiracetam Dosing in Term and Preterm Neonates

The Journal of Clinical Pharmacology, EarlyView.
Abstract Seizures are the most common neurologic emergency in neonates and are associated with significant morbidity and mortality. Current first‐line pharmacotherapy, phenobarbital, is associated with serious adverse effects, including impairment of the developing brain.
Alexis Johnson, Nolan Thomas, Max Blumenthal, Chrysanthy Ikonomidou, Sin Yin Lim   +4 more
wiley   +1 more source

Cooperative inhibition in cytochrome P450 between a substrate and an apparent noncompetitive inhibitor. [PDF]

J Biol Chem
Hirano Y, Yoneda S, Yasuda K, Kurita N, Kawagoe F, Mikami B, Takita T, Yasukawa K, Ikushiro S, Takimoto-Kamimura M, Kittaka A, Sakaki T, Tamada T.   +12 more
europepmc   +1 more source

Correction to: “Tin-Mediated Heme Oxygenase Gene Activation and Cytochrome P450 Arachidonate Hydroxylase Inhibition in Spontaneously Hypertensive Rats”

, 1994

openalex   +1 more source