Results 71 to 80 of about 7,052 (211)

Glucosinolate and Isothiocyanate Profiles in Different Varieties of Raphanus sativus Seed via Multivariate Data Analysis

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Through HPLC–MS/MS analysis and multivariate statistics, raphani semen (RS) varieties with high functional components were screened. The white raphani semen “Xuebawang” was identified as ideal for further study due to its high bioactive content: glucoraphenin (9010.27 mg/100 g), glucoraphanin (1027.76 mg/100 g), sulforaphane (66.14 mg/100 g), and ...
Yonghua Li   +10 more
wiley   +1 more source

Effects of g-hexachlorocyclohexane and L-3,3',5- triiodothyronine on rat liver cytochrome P4502E1- dependent activity and content in relation to microsomal superoxide radical generation

open access: yesBiological Research, 2003
Liver microsomal cytochrome P4502E1-dependent p-nitrophenol (PNP) hydroxylation and expression of cytochrome P4502E1 were studied in rats subjected to g-hexachlorocyclohexane (HCCH) or L-3,3,,5-triiodothyronine (T3) administration as a possible mechanism
VIRGINIA FERNÁNDEZ   +8 more
doaj  

Intensive Production of Carboxylic Acids Using C. butyricum in a Membrane Bioreactor (MBR)

open access: yesFermentation, 2018
This work reports on the use of a bench-scale chemostat (CSTR) in continuous mode and of a pilot-scale membrane bioreactor (MBR) in fed-batch mode to intensively produce acetic and butyric acids using C. butyricum grown on synthetic media.
Husnul Azan Tajarudin   +4 more
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

Presence of cytochrome P450 in the Caribbean corals Siderastrea siderea and Montastraea faveolata

open access: yesCiencias Marinas, 2005
Cytochrome P450 was detected in the animal tissue of the scleractinian corals Siderastrea siderea and Montastraea faveolata collected from a reef site on the west coast of Venezuela.
E García, R Ramos, C Bastidas
doaj   +1 more source

Advances and perspectives in animal models of human hepatitis A virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li   +3 more
wiley   +1 more source

Cytochrome P450 2C24: expression, tissue distribution, high-throughput assay, and pharmacological inhibition

open access: yesActa Pharmaceutica Sinica B, 2012
Cytochrome P450 (CYP)-mediated epoxidation of arachidonic acid (AA) contributes to important biological functions, including the pain-relieving responses produced by analgesic drugs. However, the relevant epoxygenase(s) remain unidentified. Presently, we
Jun Yang   +4 more
doaj   +1 more source

The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility

open access: yesmBio, 2016
Ergosterol is a major and specific component of the fungal plasma membrane, and thus, the cytochrome P450 enzymes (Erg proteins) that catalyze ergosterol synthesis have been selected as valuable targets of azole antifungals.
Jinxing Song   +7 more
doaj   +1 more source

Successful treatment of schizophrenia with melperone augmentation in a patient with phenotypic CYP2D6 ultrarapid metabolization: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction There are limited treatment options for people with schizophrenia with cytochrome P450 2D6 ultrarapid metabolizer status who do not respond to amisulpride.
Gahr Maximilian   +4 more
doaj   +1 more source

In Silico Screening of Plant-Derived Termiticidal Compounds Targeting Cytochrome P450 in Coptotermes spp. (Blattodea: Rhinotermitidae) for Sustainable Termite Management

open access: yesPlants
Termites of the genus Coptotermes are among the most destructive structural pests worldwide, owing to their efficient lignocellulose degradation and metabolic adaptability mediated in part by cytochrome P450 enzymes. Although numerous botanical compounds
Deepak Kumar Mahanta   +2 more
doaj   +1 more source

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