Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao +5 more
wiley +1 more source
The extreme halophilic archaeon <i>Haloferax volcanii</i> reduced Fe(III) to conserve energy from extracellular electron transfer. [PDF]
Miao Y, Yang F, Yu J, Peng P, Zhao F.
europepmc +1 more source
The Reactive Sulfhydryl Groups of Microsomal Cytochrome Reductase
openaire +2 more sources
Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
Genome-based analysis of Bacillus velezensis Bm3 isolated from a vulnerable dioxin-contaminated site in central Syria reveals mechanisms of dioxin degradation. [PDF]
Mahfouz S +3 more
europepmc +1 more source
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang +6 more
wiley +1 more source
Targeting Ferroptosis and Cuproptosis for Antimicrobial Control in Postharvest Preservation. [PDF]
Feng Y +4 more
europepmc +1 more source
A novel <i>Schinkia</i> sp. respires nitrous oxide over a broad pH range. [PDF]
He G +6 more
europepmc +1 more source
Alloimperatorin attenuates lung tumor progression by targeting oxidative stress and nuclear kappa B factor/Nrf2 pathway dysregulation. [PDF]
Xiao G, Liu Z, Xie X, Zeng Q, Chen L.
europepmc +1 more source
Dietary-Driven Gene Expansion. [PDF]
Ingelman-Sundberg M.
europepmc +1 more source

