Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti +9 more
wiley +2 more sources
Harnessing synthetic circuits to illuminate microbial electron transfer: a perspective on engineered metabolism. [PDF]
Apollon W, Ghosh S, Kamaraj S-K.
europepmc +1 more source
Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt +4 more
wiley +1 more source
Light‐Activated Isolation of High‐Quality Mitochondria for Therapeutic Transplantation
The Light‐Activated Mitochondrial Isolation (LAMI) platform enables the selective and non‐destructive isolation of high‐purity, metabolically active mitochondria. By integrating modular, ligand‐programmable magnetic probes with photo‐cleavable release, LAMI overcomes long‐standing limitations of conventional isolation methods and provides a robust ...
Hui Liu +12 more
wiley +2 more sources
Commentary: Electron transport across the cell envelope via multiheme c-type cytochromes in <i>Geobacter sulfurreducens</i>. [PDF]
Lovley DR.
europepmc +1 more source
Ghost-rocks' microbiota: metagenomic insights into their influence on the biogeochemistry of karstic cave and groundwater. [PDF]
Peugnet G +8 more
europepmc +1 more source
Mavacamten toxicity, hepatic dysfunction, and rifampicin: cause or coincidence? [PDF]
Mapelli M, Costantino S, Maragna R.
europepmc +1 more source
50 Years of Giese Reaction - a Personal View. [PDF]
Spichty M +4 more
europepmc +1 more source
H<sup>+</sup>-capacitor and ATP production in obligate alkaliphilic <i>Bacillaceae</i>: insights into cytochrome <i>c</i> and H<sup>+</sup> transport mechanisms. [PDF]
Yumoto I.
europepmc +1 more source
Pharmacogenes Associated with Suicidal Behavior: Addressing a Potential Therapeutic Window. [PDF]
Becerra López JA +2 more
europepmc +1 more source

