Results 231 to 240 of about 101,816 (333)

Medications, epilepsy and climate change: Added layers of complexity

British Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi, Seyhmus Gavas, Sanjay M. Sisodiya   +2 more
wiley   +1 more source

Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex in <i>Sideroxydans lithotrophicus</i> ES-1. [PDF]

Appl Environ Microbiol
Keffer JL, Zhou N, Rushworth DD, Yu Y, Chan CS.   +4 more
europepmc   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Xanthocillin X Dimethyl Ether Exhibits Anti-Proliferative Effect on Triple-Negative Breast Cancer by Depletion of Mitochondrial Heme. [PDF]

Mar Drugs
Du J, Zhang X, Guo K, Lin W, Lan W, Wang Z, Shi M, Huang Z, Li H, Ma W.   +9 more
europepmc   +1 more source

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

BioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

Cytochrome "nanowires" are physically limited to sub-picoamp currents that suffice for cellular respiration. [PDF]

Front Chem
Guberman-Pfeffer MJ, Herron CL.
europepmc   +1 more source

Detecting Excess Biofilm Thickness in Microbial Electrolysis Cells by Real‐Time In‐Situ Biofilm Monitoring

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Long‐term stable operation of bioelectrochemical systems (BES) presupposes the avoidance of mass transfer limitations of the electroactive biofilm. Excessive pH‐gradients from bulk to electrode interface or substrate limitations of the electroactive biofilm are known to diminish the electrical performance of BES.
Andreas Netsch, Inka Latussek, Harald Horn, Michael Wagner   +3 more
wiley   +1 more source

Overexpression of multi-heme C-type cytochromes

BioTechniques, 2005
Liang Shi, Jiann-Trzwo Lin, Lye M. Markillie, Thomas C. Squier, Brian S. Hooker   +4 more
doaj   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen, Shijie Shangguan, Zhongyu Lin, Xuemei Zeng, Siew Yin Chan, Xian Qin, Shuangqian Yan   +6 more
wiley   +1 more source

Novel Insights on Extracellular Electron Transfer Networks in the Desulfovibrionaceae Family: Unveiling the Potential Significance of Horizontal Gene Transfer. [PDF]

Microorganisms
Gonzalez V, Abarca-Hurtado J, Arancibia A, Claverías F, Guevara MR, Orellana R.   +5 more
europepmc   +1 more source