Results 251 to 260 of about 127,689 (285)

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

A rescue approach in refractory diffuse large B-cell lymphoma with obinutuzumab-redirected cytokineinduced killer cells: a first-in-human case report. [PDF]

Haematologica
Elice F, Sommaggio R, Cappuzzello E, Riva M, Tisi MC, Bernardi M, Bozza A, Catanzaro D, Chieregato K, Merlo A, Giaretta I, Pieta AD, Krampera M, Visco C, Trentin L, Visentin A, Tosetto A, Astori G, Rosato A.   +18 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Cancer Immunotherapy with Cytokine-Induced Killer Cells

Targeted Oncology, 2017
Cytokine-induced killer (CIK) cells form under certain stimulation conditions in cultures of peripheral blood mononuclear cells (PBMCs). They are a heterogeneous immune cell population and contain a high percentage of cells with a mixed T-NK phenotype (CD3+CD56+).
Juan J, Mata-Molanes, Manuel, Sureda González, Belén, Valenzuela Jiménez, Elena Mª, Martínez Navarro, Antonio, Brugarolas Masllorens   +4 more
openaire   +2 more sources

Is there a Role for Cytokine-Induced Killer Cells in Cancer Immunotherapy?

Immunotherapy, 2012
867 ISSN 1750-743X 10.2217/IMT.12.89 © 2012 Future Medicine Ltd Immunotherapy (2012) 4(9), 867–869 “There is no doubt that the use of cytokine-induced killer cells holds promise but only the future will tell us whether this relatively simple form of adoptive cellular immunotherapy will really have an impact on the still dismal prognosis of patients ...
Rutella, Sergio, Locatelli, Franco
openaire   +2 more sources

Promising immunotherapy: Highlighting cytokine‐induced killer cells

Journal of Cellular Biochemistry, 2018
AbstractFor many years, cancer therapy has appeared to be a challenging issue for researchers and physicians. By the introduction of novel methods in immunotherapy, the prospect of cancer therapy even more explained than before. Cytokine‐induced killer (CIK) cell‐based immunotherapy demonstrated to have potentiality in improving clinical outcomes and ...
Solmaz Shirjang, Nazila Alizadeh, Behzad Mansoori, Ata Mahmoodpoor, Hossein Samadi Kafil, Mohammad Hojjat‐Farsangi, Mehdi Yousefi   +6 more
openaire   +2 more sources

Cytokine Induced Killer (CIK) cells for the treatment of haematological neoplasms

Immunology Letters, 2013
Cytokine Induced Killer (CIK) cells are in vitro activated human CD8 T cells which have maintained several characteristics of T-EMRA cells and additionally acquired non specific anti tumoral cytotoxicity and CD56 overexpression, thus representing a cell population with double T and NK phenotype.
Martino Introna, Josée Golay, Alessandro Rambaldi   +2 more
exaly   +3 more sources

The Therapeutic Potential of Cytokine-Induced Killer in Patients with Cancer

Journal of Interferon & Cytokine Research
Despite the promising results of immunotherapy, further experiments need to be considered because of several factors ranging from physical barriers to off-tumor adverse effects. It is surprising that adoptive cellular immunotherapy, particularly dendritic cell and cytokine-induced killer (DC-CIK) therapy, is far less emphasized in the treatment of ...
Sixun Zhong, Yan Zhang, Xiaomin Lu, Vafa Meftahpour   +3 more
openaire   +2 more sources

Progenitor-predominant exhaustion in cytokine-induced killers reveals TIM-3 as a superior target for enhancing cytokine-induced killer cytotoxicity

Journal of Leukocyte Biology
Abstract Precursor exhausted and terminally exhausted T cells (Tpex and Tex) are associated with immune checkpoints; T-cell checkpoint blockade may improve patient survival. We assessed cytotoxic activity and PD-1/TIM-3 expressions of CD3+CD8+CD56+ T cells (NK-like T) in cytokine-induced killer (CIK) cells across exhaustion states. We
Jian Wang, Qin Wang, Jiahui Zhou, Li Zhou, Xiubao Ren, Feng Wei   +5 more
openaire   +2 more sources

Clinical expansion of cytokine induced killer (CIK) cells

ISBT Science Series, 2012
Cytokine induced killer (CIK) cells are polyclonal T cells that can be expanded from marrow or peripheral blood lymphocytes with potent non‐MHC‐restricted cytotoxicity against a variety of tumor target cells. Earlier work had established the superiority of CIK cells over LAK cells in terms expansion and cytotoxicity.
M. B. C. Koh, Y. Ching Linn
openaire   +1 more source