Results 141 to 150 of about 1,308,694 (239)

Inactivated mycobacterium paragordonae delivered via microneedle patches as a novel tuberculosis booster vaccine. [PDF]

open access: yesHum Vaccin Immunother
Lee M   +8 more
europepmc   +1 more source

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel   +15 more
wiley   +1 more source

Circadian synchronization differentially modifies cytokine-mediated transcriptomic remodeling and cell death in INS-1 cells and mouse islets. [PDF]

open access: yesiScience
Andersen PAK   +9 more
europepmc   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan   +7 more
wiley   +1 more source

Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn’s disease [PDF]

open access: yes, 2018
Bonkowski, Erin   +12 more
core   +2 more sources

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

open access: yesAdvanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han   +7 more
wiley   +1 more source

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