Cytokine expression in malaria-infected non-human primate placentas [PDF]
Malaria parasites are known to mediate the induction of inflammatory immune responses at the maternal-foetal interface during placental malaria (PM) leading to adverse consequences like pre-term deliveries and abortions. Immunological events that take place within the malaria-infected placental micro-environment leading to retarded foetal growth and ...
arxiv
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis. [PDF]
George B. Zavoico+3 more
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This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Inflammatory cytokines induce synthesis and secretion of gro protein and a neutrophil chemotactic factor but not β2-microglobulin in human synovial cells and fibroblasts [PDF]
E.E. Golds, Patrizia Mason, P Nyirkos
openalex +1 more source
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
Human endothelial cells prolong eosinophil survival. Regulation by cytokines and glucocorticoids. [PDF]
Ana Lamas+2 more
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The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
A cytokine-enhanced viral infection model with CTL immune response, distributed delay and saturation incidence [PDF]
In this paper, we propose a delayed cytokine-enhanced viral infection model incorporating saturation incidence and immune response. We compute the basic reproduction numbers and introduce a convex cone to discuss the impact of non-negative initial data on solutions.
arxiv
An epidermal cell-derived cytokine triggers the in vivo synthesis of serum amyloid A by hepatocytes. [PDF]
Marcelo B. Sztein+2 more
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source