Results 181 to 190 of about 799,218 (270)

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

COVID-19 cytokine storm: The anger of inflammation

open access: yesCytokine, 2020
Mehdi Mahmudpour   +4 more
semanticscholar   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

Covalent On‐Cell Conjugation of Biomaterials Through Oxidative Phenolic Coupling Regulates Stem Cell Fate via Intracellular Biophysical Programming

open access: yesAdvanced Functional Materials, EarlyView.
On‐cell covalent crosslinking of hydrogel matrix to the membrane of a single cell using droplet microfluidics enables mechanotransduction and influences stem cell fate. This newly established approach influences stem cell fate, independent of YAP/TAZ mechanotransduction and non‐covalent reversible binding ligands yet by various intracellular ...
Castro Johnbosco   +6 more
wiley   +1 more source

Pathophysiology of Cytokines

open access: bronze, 1986
Takashi Ikejima, Charles A. Dinarello
openalex   +2 more sources

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

open access: yesAdvanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier   +26 more
wiley   +1 more source

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