Results 201 to 210 of about 2,225,287 (343)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice

, 2021
Tejas R. Karhadkar, Darrell Pilling, Richard H. Gomer   +2 more
openalex   +2 more sources

Children with extended oligoarticular and polyarticular juvenile idiopathic arthritis have alterations in B and T follicular cell subsets in peripheral blood and a cytokine profile sustaining B cell activation [PDF]

, 2023
C. Tomé, Filipa Oliveira‐Ramos, Raquel Campanilho‐Marques, Ana Filipa Mourão, Sandra Sousa, Cláudia Marques, Ana Teresa Melo, R. L. Teixeira, Ana Paula Martins, Sofia Moeda, Patrícia Costa‐Reis, Rita Torres, Matilde Bandeira, Helena Fonseca, Miroslava Gonçalves, María José Santos, Luís Graça, João Eurico Fonseca, R. A. Moura   +18 more
openalex   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Anticancer Drug 2-Methoxyestradiol Protects against Renal Ischemia/Reperfusion Injury by Reducing Inflammatory Cytokines Expression [PDF]

, 2014
Ying-Yin Chen, Ching‐Hua Yeh, Edmund Cheung So, Ding‐Ping Sun, Li-Yun Wang, Chung‐Hsi Hsing   +5 more
openalex   +1 more source

Arginine-Glycine-Aspartic Acid-anchored Curcumin-based NanotherapeuticsInhibit Pyroptosis-induced Cytokine Release Syndrome for In Vivo and In VitroSepsis Applications

, 2023
Xiaoling Xu, Wei Chen, Yi Shi, Qian Wu, Yi Lu, Lingpeng Meng, Xiaojuan Wang   +6 more
openalex   +1 more source

Cytokine levels reflect tic symptoms more prominently during mild phases [PDF]

, 2023
SuHyuk Chi, Young Eun Mok, June Kang, Jeong‐An Gim, Hans‐Jürgen Möller, Moon‐Soo Lee   +5 more
openalex   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Editorial: Cytokine dynamics in livestock: from health to pathology. [PDF]

Front Vet Sci
Alhussien MN, Sipka AS, De Matteis G, Flores-Villalva S, Hussen J.   +4 more
europepmc   +1 more source

Morinda citrifolia(Noni) Fruit Juice Reduces Inflammatory Cytokines Expression and Contributes to the Maintenance of Intestinal Mucosal Integrity in DSS Experimental Colitis [PDF]

, 2017
Beatriz Coutinho de Sousa, Juliana Reis Machado, Marcos Silva, Thiago Álvares da Costa, Javier Emílio Lazo Chica, Thatiane do Prado Degasperi, Virmondes Rodrigues, Helioswilton Sales‐Campos, Elizabeth Uber Bucek, Carlo José Freire Oliveira   +9 more
openalex   +1 more source