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Cytokine and anti-cytokine therapy for asthma
Current Allergy and Asthma Reports, 2006Cytokines play a critical role in the pathogenesis of asthma. Asthma resolution may depend on the correction of dysregulated cytokine expression, which is a characteristic feature of this chronic inflammatory disease. It is, therefore, not surprising that attempts have been made to either block cytokines present at elevated levels or to substitute ...
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Cytokines and Cytokine-Specific Therapy in Asthma
2012Asthma is increasing in prevalence worldwide. It is characterized by typical symptoms and variable airway obstruction punctuated with episodes of worsening symptoms known as exacerbations. Underlying this clinical expression of disease is airway inflammation and remodeling.
Dhananjay, Desai +1 more
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Cytokines, Cytokine Receptors and Cytokine Antibodies: Clinical Implications
1997Cytokines are produced by almost any cell and function as important mediators of cell activation, differentiation and proliferation. These diffusibile glycoproteins appear to participate in the mediation of inflammatory as well as immune reactions, and some peptides may even influence tumor growth.
E. Berti +3 more
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Anti-inflammatory Cytokines and Cytokine Antagonists
Current Pharmaceutical Design, 2000Cytokines are critical mediators of protective host responses, including defense against microbial invasion and tumorigenesis. However, the production of specific proinflammatory cytokines must be tightly regulated and compartmentalized to prevent the overzealous expression of these molecules that can culminate in unabated inflammation and tissue ...
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Cytokines and Biocompatibility
Blood Purification, 2008Issues in biocompatibility have traditionally focused on the interaction of membranes or materials with the activation of complement, red blood cell destruction, clotting dysfunctions, and platelet activation. Other studies are concerned with the replacement fluid formulations and host responses.
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Cytokines, cytokine receptors and cytokine antibodies
Melanoma Research, 1996E. Berti, R. Caputo
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