Advanced Functional Materials, EarlyView.Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier +26 more
wiley +1 more source
Cytokine receptor cluster size impacts its endocytosis and signaling. [PDF]
Proc Natl Acad Sci U S A, 2021 Salavessa L +8 more
europepmc +1 more source
A Kaposi's Sarcoma-associated Herpesvirus-encoded Cytokine Homolog (vIL-6) Activates Signaling through the Shared gp130 Receptor Subunit [PDF]
, 1997 Jaime Molden +4 more
openalex +1 more source
Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine
Advanced Functional Materials, EarlyView.Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang +5 more
wiley +1 more source
Protein abundance of the cytokine receptor γc controls the thymic generation of innate-like T cells. [PDF]
Cell Mol Life Sci, 2021 Park JY +4 more
europepmc +1 more source
Impaired Cytokine Signaling in Mice Lacking the IL-1 Receptor-Associated Kinase [PDF]
, 1999 James A. Thomas +7 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
Advanced Functional Materials, EarlyView.MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee +6 more
wiley +1 more source
Reconstruction of Intercellular Signaling Network by Cytokine-Receptor Interactions. [PDF]
Iran J Biotechnol, 2021 Azadian S +3 more
europepmc +1 more source
Cytokines and diseases. Interleukin-2 and its receptor in adult T cell leukemia.
, 1991 Takashi Uchiyama
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Advanced Functional Materials, EarlyView.A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi +11 more
wiley +1 more source