Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells. [PDF]
Yoshikawa T+11 more
europepmc +1 more source
Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivo [PDF]
Mark A. Goldsmith+6 more
openalex +1 more source
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim+8 more
wiley +1 more source
A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy. [PDF]
Hsu EJ+6 more
europepmc +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
CD20highCD138low tumor-infiltrating lymphocytes predominantly related to cytokine‒cytokine receptor interactions are associated with favorable outcomes in neuroblastoma patients. [PDF]
Qin LJ+10 more
europepmc +1 more source
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang+9 more
wiley +1 more source
Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling. [PDF]
Fields JK+17 more
europepmc +1 more source
Improved cytokine-receptor interaction prediction by exploiting the negative sample space. [PDF]
Nath A, Leier A.
europepmc +1 more source