Results 251 to 260 of about 3,715,994 (387)

The integrity of the conserved ‘WS motif’ common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction. [PDF]

, 1991
Tadaaki Miyazaki, Mitsuo Maruyama, Gen Yamada, Mariko Hatakeyama, Tadatsugu Taniguchi   +4 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

The ever-expanding role of cytokine receptor DR3 in T cells. [PDF]

Cytokine
Liman N, Lanasa D, Meylan F, Park JH.
europepmc   +1 more source

Locust Hemolymph Conveys Erythropoietin-Like Cytoprotection via Activation of the Cytokine Receptor CRLF3. [PDF]

Front Physiol, 2021
Knorr DY, Hartung D, Schneider K, Hintz L, Pies HS, Heinrich R.   +5 more
europepmc   +1 more source

FAM3 Cytokine-like Proteins, Their Putative Receptors and Signaling Pathways in Metabolic Diseases and Cancers

Jose E. Belizario, Izabela D. S. Caldeira, Bruna Moreira, João M. Occhiucci, Brant R. Burkhardt, Humberto Miguel Garay-Malpartida   +5 more
openalex   +2 more sources

Augmentation of Chemotherapy-Induced Cytokine Production by Expression of the Platelet-Activating Factor Receptor in a Human Epithelial Carcinoma Cell Line [PDF]

, 2004
Marc A. Darst, Mohammed Al‐Hassani, Tao Li, Qiaofang Yi, John M. Travers, Davina A. Lewis, Jeffrey B. Travers   +6 more
openalex   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Cytokine Receptor-like Factor 1 (CRLF1) and Its Role in Osteochondral Repair. [PDF]

Cells
Zhang F, Clair AJ, Dankert JF, Lee YJ, Campbell KA, Kirsch T.   +5 more
europepmc   +1 more source

Faculty Opinions recommendation of T cell receptor and cytokine signaling can function at different stages to establish and maintain transcriptional memory and enable T helper cell differentiation.

, 2019
Matthew E. Pipkin
openalex   +2 more sources

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source