Results 171 to 180 of about 109,140 (300)

Identifying ICAM-1 as a Therapeutic Target for Cytokine Storm in Human Macrophages Through Integrative Bioinformatics Approaches. [PDF]

Molecules
Chen S, Wu D, Zheng Z, Luo Y, Zhang L.
europepmc   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Cytokine storms in infectious diseases [PDF]

Seminars in Immunopathology, 2017
openaire   +2 more sources

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

The Interleukin Network in Sepsis: From Cytokine Storm to Clinical Applications. [PDF]

Diagnostics (Basel)
Candelli M, Sacco Fernandez M, Rozzi G, Sodero G, Piccioni A, Pignataro G, Rigante D, Franceschi F.   +7 more
europepmc   +1 more source

Coronavirus disease 2019 infection reduces EGFR‐TKI efficacy in non‐small cell lung carcinoma: Real‐world evidence from a multicenter propensity‐matched cohort

International Journal of Cancer, EarlyView.
What's New? Lung cancer patients with COVID‐19 experience significantly increased risk for severe illness and mortality. However, research addressing the effect of COVID‐19 on non‐small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) remains unknown.
Wenjie Tang, Xiaoxuan Hou, Li Li, Hanxi Zhao, Xiaoyong Tang, Wanqi Zhu, Xiaohui Yan, Jing Liu, Qian Wu, Zhu Qiao, Shanliang Hu, Mingwei Zhang, Xiaolin Li, Peng Xie   +13 more
wiley   +1 more source

Cytokine Storm in a Massively Burned Pediatric Patient. [PDF]

J Burn Care Res
Sharma M, Roach L, Bull A, Flygt L, Ballas Z, Kurjatko A, Chegondi M, Wibbenmeyer L.   +7 more
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome. [PDF]

Arthritis Rheumatol
Kaneko S, Hatano M, Shimbo A, Miyaoka F, Irabu H, Akutsu Y, Hayashi Y, Mizuta M, Nakagishi Y, Akamine K, Iwata N, Furuno K, Tanaka T, Ueno K, Fujita S, Yokoyama K, Minato T, Izawa K, Yasumi T, Matsubayashi T, Hosoya T, Nishikawa H, Fujimura J, Asano R, Sugita Y, Watanabe K, Kobayashi A, Endo T, Eguchi K, Nishikomori R, Yasuoka R, Asano T, Kanno M, Hamada K, Fujita Y, Hayashi D, Watanabe S, Shiba T, Yasuda S, Mori M, Kanegane H, Takagi M, Shimizu M.   +42 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source