Results 121 to 130 of about 1,637,423 (248)

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review

open access: yesPhytotherapy Research, EarlyView.
Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang   +8 more
wiley   +1 more source

IL-1 Family Blockade in Cytokine Storm Syndromes [PDF]

open access: yes, 2019
Interleukin-1 is a prototypic proinflammatory cytokine that is elevated in cytokine storm syndromes (CSSs), such as secondary hemophagocytic lymphohistiocytosis (sHLH) and macrophage activation syndrome (MAS). IL-1 has many pleotropic and redundant roles in both innate and adaptive immune responses. Blockade of IL-1 with recombinant human interleukin-1
openaire   +2 more sources

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

The association between red blood cell distribution width‐to‐albumin ratio and risk of insomnia: A cross‐sectional analysis of National Health and Nutrition Examination Survey and Chinese clinical data

open access: yesSleep Research, EarlyView.
Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma   +7 more
wiley   +1 more source

Photobiomodulation Reduces the Cytokine Storm Syndrome Associated with COVID-19 in the Zebrafish Model. [PDF]

open access: yesInt J Mol Sci, 2023
Rosa IF   +41 more
europepmc   +1 more source

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

open access: yesSmall, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung   +2 more
wiley   +1 more source

Pentoxifylline Effects on Hospitalized COVID-19 Patients with Cytokine Storm Syndrome: A Randomized Clinical Trial. [PDF]

open access: yesPharmaceuticals (Basel), 2023
Sarhan RM   +8 more
europepmc   +1 more source

Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way

open access: yesmBio
Hyperactivation of pro-inflammatory type 1 cytokines (e.g., tumor necrosis factor alpha [TNF-α] and interferon gamma [IFN-γ]) mirrors the inflammation of coronavirus disease 2019. Helminths could alleviate excessive immune responses.
Zengguo Cao   +7 more
doaj   +1 more source

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