Enhancement of OVA-induced murine lung eosinophilia by co-exposure to contamination levels of LPS in Asian sand dust and heated dust. [PDF]
BackgroundA previous study has shown that the aggravation of Asian sand dust (ASD) on ovalbumin (OVA)-induced lung eosinphilia was more severe in lipopolysaccharide (LPS)-rich ASD than in SiO2-rich ASD.
He, Miao+9 more
core +3 more sources
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Distinct cytokine profiles across trajectories of self-perceived cognitive impairment among early-stage breast cancer survivors. [PDF]
The aim of the current study is to identify distinct cytokine profiles in relation to self-perceived cognitive trajectories. In our study cohort (n = 128), early-stage breast cancer patients were categorized into no impairment reported, acute ...
Chan, Alexandre+3 more
core +1 more source
Altered expression of cytokines in mice infected intranasally with two syncytial variants of Herpes simplex virus type 1 [PDF]
Immune evasion strategies are important for the onset and the maintenance of viral infections. Many viruses have evolved mechanisms to counteract or suppress the host immune response.
Adler+31 more
core +2 more sources
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Cytokines and Febrile Convulsions
The production of pro-inflammatory cytokines (IL-1B, IL-6, and TNF-a), and anti-inflammatory cytokine IL-10 by peripheral blood mononuclear cells (PBMC) from 13 children 2 weeks after a febrile convulsion and in 11 without a history of febrile convulsion,
J Gordon Millichap
doaj +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Inflammatory Cytokine Expressions of the Subacromial Bursitis and Glenohumeral Joint Synovitis in the Patients with Full Thickness Rotator Cuff Tear [PDF]
Sung Kyu Kim+5 more
openalex +1 more source
IL17RA or IL17RCTh17 cells and others Mucosal tissues, epithelial and endothelial cells Proinflammatory; protective immunity in lung; tight junction integrity; promotes mobilization of neutrophils and cytokine production by epithelial cells; promotes angiogenesis↓ = susceptibility to extracellular pathogens↑ = exacerbates organ-specific autoimmune ...
Daniel J. Cua, Cristina M. Tato
openaire +6 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source