Results 81 to 90 of about 1,315,320 (313)
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Antibacterial Activities of Oxyprenylated Chalcones and Napthtoquinone against
Natural Product Communications, 2014 In this study, we synthesized and characterized the antibacterial activity of three naturally occurring oxyprenylated chalcones {xinjiachalcone A ( 1 ), (2 E )-1-{2,6-dihydroxy-4-[(3-methylbut-2-enyl)oxy]phenyl}-3-(4-hydroxyphenyl)prop-2-en-1-one ( 2 ), (
Charles Bodet +7 more
doaj +1 more source
Cancer Medicine, 2020 Background Pancreatic cancer patients are at risk for venous thromboembolism (VTE); the value of thromboprophylaxis has not been definitively established.
Saroj Vadhan‐Raj +10 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Cytokines and pregnancy in rheumatic disease [PDF]
, 2006 Cytokines are important mediators involved in the successful outcome of pregnancy. The concept of pregnancy as biased toward a Th2 immune response states that Th1 type cytokines are associated with pregnancy failure and that Th2 cytokines are protective ...
Förger, Frauke +5 more
core +1 more source
ОЦЕНКА ИММУНОЛОГИЧЕСКИХ ПОКАЗАТЕЛЕЙ ПРИ ЛЕКАРСТВЕННОЙ УСТОЙЧИВОСТИ ВИЧ НА ФОНЕ ВААРТ [PDF]
, 2020 The aim of the study is to identify immunological markers that may be important to predict drug resistance of patients to HAART.Materials and methods. Examined 53 patients with HIV infection, virological and immunological HAART failure.
L. F. Sclar +13 more
core +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature [PDF]
, 2010 Cytokines may influence brain activities especially during stressful conditions, and elevated levels of IL-6 and C-reactive protein have been pointed out in subjects with Major Depression.
Pozzi, Gino, Janiri, Luigi
core
Breast Cancer: Basic and Clinical ResearchIntroduction: The purpose of this study was to determine the prognostic utility of vitamin D concentrations and BMI (body mass index) values and the systemic immune-inflammation index (SII), the systemic inflammation response index (SIRI) and the pan ...
Beata Kotowicz +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source