Results 71 to 80 of about 1,310,032 (313)
Cytokines: Sensors of the nervous system
, 2012 The central nervous system (CNS) and the immune system share multiple chemical messengers ranging from small molecules, such as corticotropin-releasing factor (CRF) to large proteins, such as cytokines and growth factors.
Fafutis-Morris, M. +1 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
, 2008 This book opens a new page of neuroimmunebiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease.
Korneva, E. A.(Elena Andreevna) +1 more
core
Inflammatory cytokines and atrial fibrillation: current and prospective views
, 2010 Hadi AR Hadi, Alawi A Alsheikh-Ali, Wael AL Mahmeed, Jassim M Al SuwaidiInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab EmiratesAbstract: Atrial fibrillation (AF) is the most common sustained arrhythmia and a ­ ...
Hadi AR Hadi +4 more
core +1 more source
Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination. [PDF]
, 2012 : Heparin-binding haemagglutinin (HBHA)-specific immune responses have been linked to protection against tuberculosis (TB). We investigated the hypothesis that BCG vaccination of human infants primes an HBHA-specific response, using multiplex to measure ...
Smith, SG +9 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Antibacterial Activities of Oxyprenylated Chalcones and Napthtoquinone against
Natural Product Communications, 2014 In this study, we synthesized and characterized the antibacterial activity of three naturally occurring oxyprenylated chalcones {xinjiachalcone A ( 1 ), (2 E )-1-{2,6-dihydroxy-4-[(3-methylbut-2-enyl)oxy]phenyl}-3-(4-hydroxyphenyl)prop-2-en-1-one ( 2 ), (
Charles Bodet +7 more
doaj +1 more source
Cancer Medicine, 2020 Background Pancreatic cancer patients are at risk for venous thromboembolism (VTE); the value of thromboprophylaxis has not been definitively established.
Saroj Vadhan‐Raj +10 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Virus encoded cytokines and cytokine receptors
Parasitology, 1997 In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
M, Barry, G, McFadden
openaire +2 more sources