Results 101 to 110 of about 1,315,320 (313)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Unexpectedly decreased plasma cytokines in patients with chronic back pain [PDF]

, 2018
Simona Capossela,1 David Pavlicek,1 Alessandro Bertolo,1 Gunther Landmann,2 Jivko V Stoyanov1 1Swiss Paraplegic Research, Nottwil, Switzerland; 2Centre for Pain Medicine, Swiss Paraplegic Centre, Nottwil, Switzerland Introduction: Chronic back pain is ...
Landmann G, Stoyanov JV, Pavlicek D, Bertolo A, Capossela S   +4 more
core  

Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells - Redundancy or specificity of neuroimmunoendocrine modulators? [PDF]

, 2004
Objective: This comparative in vitro study examined the effects of all known gp130 cytokines on murine corticotroph AtT-20 cell function. Methods: Cytokines were tested at equimolar concentrations from 0.078 to 10 nM.
Kopp, F. B., Isele, N. B., Cengic, N., Weber, M. M., Engelhardt, D., Spottl, G., Senaldi, G., Auernhammer, Christoph J., Dorn, F., Vlotides, G.   +9 more
core   +1 more source

SnapShot: Cytokines I

Cell, 2008
IL17RA or IL17RCTh17 cells and others Mucosal tissues, epithelial and endothelial cells Proinflammatory; protective immunity in lung; tight junction integrity; promotes mobilization of neutrophils and cytokine production by epithelial cells; promotes angiogenesis↓ = susceptibility to extracellular pathogens↑ = exacerbates organ-specific autoimmune ...
Tato, Cristina M., Cua, Daniel J.
openaire   +5 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Th1 and Th2 cytokines are elevated in HCV-infected SVR(-) patients treated with interferon-alpha [PDF]

, 2010
[[abstract]]Interferon-alpha-based treatment is a standard therapy to cure hepatitis C virus-infected patients. However, the reasons for the failure of interferon-alpha treatment in some patients have not been fully elucidated.
Wan, L (Wan, Lei); Kung, YJ (Kung, Yung-Jen); Lin, YJ (Lin, Ying-Ju); Liao, CC (Liao, Chiu-Chu); Sheu, JJC (Sheu, Jim J. C.); Tsai, YS (Tsai, Yuhsin); Lai, HC (Lai, Hsueh-Chou); Peng, CY (Peng, Cheng-Yuan); Tsai, FJ (Tsai, Fuu-Jen)
core   +1 more source

Comparative analysis of cutaneous features of psoriasis in acute and chronic imiquimod-induced mouse models

Scientific Reports
Psoriasis is a chronic inflammatory skin disorder influenced by genetic and environmental factors. The imiquimod (IMQ)-induced mouse model is widely used to study psoriasis-like skin inflammation.
Emma Fraillon, Jean-François Jégou, Hanitriniaina Rabeony, Jean-Claude Lecron, Nicolas Lebonvallet, Emilie Marie-Joseph, Audrey Josset-Lamaugarny, Géraldine Aimond, Laurent Misery, Franck Morel, Fabien P. Chevalier, Bérengère Fromy   +11 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cytokines in hepatitis C-infected patients with or without opioid maintenance therapy [PDF]

Objective: Both chronic hepatitis C virus (HCV) infection and opioids cause altered blood levels of cytokines. Previous studies have investigated levels of selected groups of cytokines in patients on opioid maintenance treatment.
Bramness, Jørgen Gustav, Øiesvold, Terje, Mollnes, Tom Eirik, Berk, Michael, Kristiansen, Magnhild Gangsøy, Brekke, Ole Lars, Nygaard-Odeh, Kristin, Soloy-Nilsen, Hedda   +7 more
core   +1 more source

Comparative Analysis of Genetically Engineered Immunodeficient Mouse Strains as Recipients for Human Myoblast Transplantation

Cell Transplantation, 2005
The development of an optimized animal model for the in vivo analysis of human muscle cells remains an important goal in the search of therapy for muscular dystrophy.
Suse D. Silva-Barbosa, Gillian S. Butler-Browne, James P. Di Santo, Vincent Mouly   +3 more
doaj   +1 more source