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Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source
CD8 regulatory T cell therapy in transplantation: a new path to clinical success? [PDF]
Muller YD, Zuber J.
europepmc +1 more source
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang +16 more
wiley +1 more source
Inhibition of neutrophil infiltration and NETs formation ameliorates neuropsychiatric and renal dysfunction in MRL/lpr mice with lupus. [PDF]
Deng Y +15 more
europepmc +1 more source
Editorial: Adaptive immune regulation of non-alcoholic steatohepatitis (NASH). [PDF]
Wang H.
europepmc +1 more source
Orally Administered Porcine Intestinal Lactobacilli Improve the Respiratory Innate Immune Response Against <i>Streptococcus pneumoniae</i>. [PDF]
Fukuyama K +7 more
europepmc +1 more source
Case Report: Localized hyperinflammatory response in the bulla after mosquito bites in a patient with systemic lupus erythematosus. [PDF]
Bian S, Huang C, Wen L.
europepmc +1 more source
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Cytokines in inflammatory bowel disease
Nature Reviews Immunology, 2014Markus Neurath
exaly +2 more sources

