Results 191 to 200 of about 1,114,713 (255)
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Strategies for targeting cytokines in inflammatory bowel disease
Nature Reviews ImmunologyMarkus Neurath
exaly +2 more sources
Cytokines and chemokines in clinical immunology
Clinical Immunology Newsletter, 1997Deshratn Asthana, Mary Ann Fletcher
exaly +2 more sources
Cytokines as immunological adjuvants
Vaccine, 1992Various cytokines have been shown to be effective immunological adjuvants in a variety of model systems, enhancing protection induced by viral, bacterial and parasitic vaccines, and increasing parameters of immunity in tumour immunization models and in clinical trials.
A W, Heath, J H, Playfair
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Recombinant cytokines as immunological adjuvants
Immunology & Cell Biology, 1993SummaryThis paper describes the bacterial expression and purification of bioactive recombinant ovine interleukin‐2 (rovIL‐2), interleukin‐lα (rovlL‐lα) and tumour necrosis factor α. These purified proteins had specific activities in appropriate bioassays of 1 × 107, 1 times; 107 and 1 × 105 U/mg, respectively.
Nash, AD +7 more
openaire +5 more sources
Cancer immunology research, 2022
Immune checkpoint blockade is therapeutically successful for many patients across multiple cancer types. However, immune-related adverse events (irAE) frequently occur and can sometimes be life threatening.
Robin Reschke +6 more
semanticscholar +1 more source
Immune checkpoint blockade is therapeutically successful for many patients across multiple cancer types. However, immune-related adverse events (irAE) frequently occur and can sometimes be life threatening.
Robin Reschke +6 more
semanticscholar +1 more source
Cytokines in rheumatoid arthritis — shaping the immunological landscape
Nature Reviews Rheumatology, 2015Cytokine-mediated pathways are central to the pathogenesis of rheumatoid arthritis (RA). The purpose of this short Opinion article is to briefly overview the roles of cytokine families in the various phases and tissue compartments of this disease. In particular, we consider the combinatorial role played by cytokines in mediating the overlapping innate ...
McInnes IB, Buckley CD, Isaacs JD
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Review of biologics in allergy and immunology.
Journal of Allergy and Clinical Immunology, 2022Biologics or molecularly targeted drugs are often highly effective for the treatment of allergic diseases and other immunologic disorders, and they are relatively safe for short-term use as compared with conventional approaches such as the systemic use ...
H. Morita, K. Matsumoto, H. Saito
semanticscholar +1 more source
Immunological aspects of ovarian function: role of the cytokines
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995Interaction between the immune system and reproduction is multiple. Either directly or indirectly through their products, immune cells are associated with the regulation of every level of the hypothalamus-pituitary-ovarian axis. Immune cells are present in the ovaries and their numbers increase during the cycle.
D, Vinatier +5 more
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Immunology of IL-12: An update on functional activities and implications for disease
EXCLI Journal : Experimental and Clinical Sciences, 2020As its first identified member, Interleukin-12 (IL-12) named a whole family of cytokines. In response to pathogens, the heterodimeric protein, consisting of the two subunits p35 and p40, is secreted by phagocytic cells.
K. Ullrich +5 more
semanticscholar +1 more source